Macrophage polarization in bacterial infections

M Benoit, B Desnues, JL Mege - The Journal of Immunology, 2008 - journals.aai.org
Converging studies have shown that M1 and M2 macrophages are functionally polarized in
response to microorganisms and host mediators. Gene expression profiling of macrophages …

Uncovering the Hidden Credentials of Brucella Virulence

RM Roop, IS Barton, D Hopersberger… - … and Molecular Biology …, 2021 - Am Soc Microbiol
Bacteria in the genus Brucella are important human and veterinary pathogens. The abortion
and infertility they cause in food animals produce economic hardships in areas where the …

Interactions of the Human Pathogenic Brucella Species with Their Hosts

VL Atluri, MN Xavier, MF de Jong… - Annual review of …, 2011 - annualreviews.org
Brucellosis is a zoonotic infection caused primarily by the bacterial pathogens Brucella
melitensis and B. abortus. It is acquired by consumption of unpasteurized dairy products or …

An evolutionary strategy for a stealthy intracellular Brucella pathogen

A Martirosyan, E Moreno, JP Gorvel - Immunological reviews, 2011 - Wiley Online Library
Brucella is an intracellular bacterial pathogen that causes abortion and infertility in mammals
and leads to a debilitating febrile illness that can progress into a long lasting disease with …

Internal affairs: investigating the Brucella intracellular lifestyle

K von Bargen, JP Gorvel… - FEMS microbiology …, 2012 - academic.oup.com
Bacteria of the genus Brucella are Gram-negative pathogens of several animal species that
cause a zoonotic disease in humans known as brucellosis or Malta fever. Within their hosts …

[HTML][HTML] Establishment of Chronic Infection: Brucella's Stealth Strategy

W Ahmed, K Zheng, ZF Liu - Frontiers in cellular and infection …, 2016 - frontiersin.org
Brucella is a facultative intracellular pathogen that causes zoonotic infection known as
brucellosis which results in abortion and infertility in natural host. Humans, especially in low …

[HTML][HTML] Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis

AM Timmer, JC Timmer, MA Pence, LC Hsu… - Journal of Biological …, 2009 - ASBMB
Group A Streptococcus (GAS) is a leading human bacterial pathogen capable of producing
invasive infections even in previously healthy individuals. As frontline components of host …

[HTML][HTML] Comparative review of brucellosis in small domestic ruminants

CA Rossetti, E Maurizio, UA Rossi - Frontiers in veterinary science, 2022 - frontiersin.org
Brucella melitensis and Brucella ovis are the primary etiological agents of brucellosis in
small domestic ruminants. B. melitensis was first isolated in 1887 by David Bruce in Malta …

[HTML][HTML] Analyses of Brucella Pathogenesis, Host Immunity, and Vaccine Targets using Systems Biology and Bioinformatics

Y He - Frontiers in cellular and infection microbiology, 2012 - frontiersin.org
Brucella is a Gram-negative, facultative intracellular bacterium that causes zoonotic
brucellosis in humans and various animals. Out of 10 classified Brucella species, B …

Coxiella burnetii Inhibits Apoptosis in Human THP-1 Cells and Monkey Primary Alveolar Macrophages

DE Voth, D Howe, RA Heinzen - Infection and immunity, 2007 - Am Soc Microbiol
Coxiella burnetii, the cause of human Q fever, is an aerosol-borne, obligate intracellular
bacterium that targets host alveolar mononuclear phagocytic cells during infection. In all cell …