Pathophysiological insights into HFpEF from studies of human cardiac tissue

AU Fayyaz, M Eltony, LJ Prokop, KE Koepp… - Nature Reviews …, 2024 - nature.com
Heart failure with preserved ejection fraction (HFpEF) is a major, worldwide health-care
problem. Few therapies for HFpEF exist because the pathophysiology of this condition is …

Prediction of Donor Heart Acceptance for Transplant and Its Clinical Implications: Results From The Donor Heart Study

B Wayda, Y Weng, S Zhang, H Luikart… - Circulation: Heart …, 2023 - ahajournals.org
BACKGROUND: Despite a shortage of potential donors for heart transplant in the United
States, most potential donor hearts are discarded. We evaluated predictors of donor heart …

Donor electrocardiogram associations with cardiac dysfunction, heart transplant use, and survival: the Donor Heart Study

N Tapaskar, B Wayda, D Malinoski, H Luikart, T Groat… - Heart Failure, 2024 - jacc.org
Background Potential organ donors often exhibit abnormalities on electrocardiograms
(ECGs) after brain death, but the physiological and prognostic significance of such …

Machine perfusion of marginal donor hearts: a valuable tool, but where and for whom?

B Wayda - European Heart Journal, 2024 - academic.oup.com
This commentary refers to 'Disparities in donor heart acceptance between the USA and
Europe: clinical implications', by B. Wayda et al., https://doi. org/10.1093/eurheartj/ehad684 …

[HTML][HTML] Evolution of heart transplant donor characteristics in the 21st century: A United States single center's experience

AM Spring, C Gjelaj, S Madan, SR Patel… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Despite a record setting number of heart transplants performed annually, the national donor
shortage continues to plague transplant teams across the United States. Here we describe …

Is an ECG Even Necessary? Value of the Electrocardiogram in Donor Heart Evaluation

MS Kiernan, MM Colvin - Heart Failure, 2024 - jacc.org
Advances in goal-directed medical therapy have improved symptoms and extended life for
patients with chronic heart failure. These therapeutic gains have led to an expanding …

Just a number? Donor age and (lack of) associated reasons for heart offer refusal

AC Bhowmik, B Wayda, H Luikart, Y Weng… - The Journal of Heart and …, 2024 - Elsevier
The use of 50+ year-old donors for heart transplant (HT) is rare in the United States. We
assessed reasons for this—and whether it reflects concern about age itself or associated risk …

Single-nuclei transcriptome of brain-dead donor heart with long QT syndrome revealed neuronal modulation of cardiac immunity

Z Wen, S Shuai, Y Feng, Z Wang, J Wu, C Wu, M Tian - 2024 - researchsquare.com
Background: Brain dead (BD) donor hearts with long QT syndrome (LQTS) showed
accelerated cardiac allograft vasculopathy (CAV). We determine the differences between …

[引用][C] The Importance of Randomized, Controlled Trials in the Care of Organ Donors.

KK Khush - The New England Journal of Medicine, 2023 - europepmc.org
The Importance of Randomized, Controlled Trials in the Care of Organ Donors. - Abstract -
Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About Tools …