Hemorrhage caused by snake venom metalloproteinases: a journey of discovery and understanding
The historical development of discoveries and conceptual frames for understanding the
hemorrhagic activity induced by viperid snake venoms and by hemorrhagic …
hemorrhagic activity induced by viperid snake venoms and by hemorrhagic …
[HTML][HTML] Snake venom metalloproteinases (SVMPs): a structure-function update
Snake venom metalloproteinases (SVMPs) represent a diverse group of multi-domain
proteins with several biological activities such as the ability to induce hemorrhage …
proteins with several biological activities such as the ability to induce hemorrhage …
Metalloproteases affecting blood coagulation, fibrinolysis and platelet aggregation from snake venoms: Definition and nomenclature of interaction sites
Snake venom metalloproteases, in addition to their contribution to the digestion of the prey,
affect various physiological functions by cleaving specific proteins. They exhibit their …
affect various physiological functions by cleaving specific proteins. They exhibit their …
Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases
Hemorrhage is one of the most significant effects in envenomings induced by viperid
snakebites. Damage to the microvasculature, induced by snake venom metalloproteinases …
snakebites. Damage to the microvasculature, induced by snake venom metalloproteinases …
Haemostatically active proteins in snake venoms
T Sajevic, A Leonardi, I Križaj - Toxicon, 2011 - Elsevier
Snake venom proteins that affect the haemostatic system can cause (a) lowering of blood
coagulability,(b) damage to blood vessels, resulting in bleeding,(c) secondary effects of …
coagulability,(b) damage to blood vessels, resulting in bleeding,(c) secondary effects of …
A comprehensive view of the structural and functional alterations of extracellular matrix by snake venom metalloproteinases (SVMPs): Novel perspectives on the …
Snake venom metalloproteinases (SVMPs) affect the extracellular matrix (ECM) in multiple
and complex ways. Previously, the combination of various methodological platforms …
and complex ways. Previously, the combination of various methodological platforms …
[HTML][HTML] Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII …
LA Freitas-de-Sousa, DR Amazonas, LF Sousa… - Biochimie, 2015 - Elsevier
Comparisons between venoms from snakes kept under captivity or collected at the natural
environment are of fundamental importance in order to obtain effective antivenoms to treat …
environment are of fundamental importance in order to obtain effective antivenoms to treat …
Role of collagens and perlecan in microvascular stability: exploring the mechanism of capillary vessel damage by snake venom metalloproteinases
T Escalante, N Ortiz, A Rucavado, EF Sanchez… - PloS one, 2011 - journals.plos.org
Hemorrhage is a clinically important manifestation of viperid snakebite envenomings, and is
induced by snake venom metalloproteinases (SVMPs). Hemorrhagic and non-hemorrhagic …
induced by snake venom metalloproteinases (SVMPs). Hemorrhagic and non-hemorrhagic …
Snake venom components in medicine: From the symbolic rod of Asclepius to tangible medical research and application
MI Estevão-Costa, R Sanz-Soler… - The international journal …, 2018 - Elsevier
Both mythologically and logically, snakes have always fascinated man. Snakes have
attracted both awe and fear not only because of the elegant movement of their limbless …
attracted both awe and fear not only because of the elegant movement of their limbless …
Snake venom disintegrins and cell migration
HS Selistre-de-Araujo, CLS Pontes, CF Montenegro… - Toxins, 2010 - mdpi.com
Cell migration is a key process for the defense of pluricellular organisms against pathogens,
and it involves a set of surface receptors acting in an ordered fashion to contribute …
and it involves a set of surface receptors acting in an ordered fashion to contribute …