[HTML][HTML] Fatty acids and evolving roles of their proteins in neurological, cardiovascular disorders and cancers
The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …
Role of oleic acid in immune system; mechanism of action; a review
C Carrillo Pérez, MM Cavia Camarero… - … , 2012, v. 27, n. 4 (julio …, 2012 - riubu.ubu.es
Introduction: Although n-3 polyunsaturated fatty acids have been widely described as
antiinflammatory fats, little is known about the role of oleic acid in immune system. Aim: The …
antiinflammatory fats, little is known about the role of oleic acid in immune system. Aim: The …
The role of nutrients in protecting mitochondrial function and neurotransmitter signaling: implications for the treatment of depression, PTSD, and suicidal behaviors
J Du, M Zhu, H Bao, B Li, Y Dong, C Xiao… - Critical reviews in …, 2016 - Taylor & Francis
Numerous studies have linked severe stress to the development of major depressive
disorder (MDD) and suicidal behaviors. Furthermore, recent preclinical studies from our …
disorder (MDD) and suicidal behaviors. Furthermore, recent preclinical studies from our …
[PDF][PDF] Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent‐resistant membranes
Sphingolipids are important structural components of cell membranes and act as critical
regulators of cell function by modulating intracellular signaling pathways. Specific …
regulators of cell function by modulating intracellular signaling pathways. Specific …
n-3 polyunsaturated fatty acids suppress the localization and activation of signaling proteins at the immunological synapse in murine CD4+ T cells by affecting lipid raft …
W Kim, YY Fan, R Barhoumi, R Smith… - The Journal of …, 2008 - journals.aai.org
The molecular properties of immunosuppressive n-3 polyunsaturated fatty acids (PUFA)
have not been fully elucidated. Using CD4+ T cells from wild-type control and fat-1 …
have not been fully elucidated. Using CD4+ T cells from wild-type control and fat-1 …
Spatial organization of transmembrane receptor signalling
I Bethani, SS Skånland, I Dikic, A Acker‐Palmer - The EMBO journal, 2010 - embopress.org
The spatial organization of transmembrane receptors is a critical step in signal transduction
and receptor trafficking in cells. Transmembrane receptors engage in lateral homotypic and …
and receptor trafficking in cells. Transmembrane receptors engage in lateral homotypic and …
Fish oil lipid emulsions and immune response: what clinicians need to know
DL Waitzberg, RS Torrinhas - Nutrition in Clinical Practice, 2009 - Wiley Online Library
Current evidence indicates that ω‐3 polyunsaturated fatty acids (PUFAs), particularly
eicosapentaenoic acid and docosahexaenoic acid found in fish oil, can prevent the …
eicosapentaenoic acid and docosahexaenoic acid found in fish oil, can prevent the …
A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines
T Puig, H Aguilar, S Cufí, G Oliveras, C Turrado… - Breast Cancer …, 2011 - Springer
Abstract Introduction Inhibiting the enzyme Fatty Acid Synthase (FASN) leads to apoptosis of
breast carcinoma cells, and this is linked to human epidermal growth factor receptor 2 …
breast carcinoma cells, and this is linked to human epidermal growth factor receptor 2 …
Cholesterol is found to reside in the center of a polyunsaturated lipid membrane
Previously, we reported neutron diffraction studies on the depth of cholesterol in
phosphatidylcholine (PC) bilayers with varying amounts of acyl chain unsaturation [Harroun …
phosphatidylcholine (PC) bilayers with varying amounts of acyl chain unsaturation [Harroun …
Rafts making and rafts braking: how plant flavonoids may control membrane heterogeneity
YS Tarahovsky, EN Muzafarov, YA Kim - Molecular and cellular …, 2008 - Springer
Plant flavonoids are not only known as powerful antioxidants, but also as cell metabolism
regulators. It has been postulated that they are able to control cell signal pathways by …
regulators. It has been postulated that they are able to control cell signal pathways by …