[HTML][HTML] The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies
M Butnariu, C Quispe, J Herrera-Bravo, P Helon… - Biomedicine & …, 2022 - Elsevier
Thymoquinone (TQ) is a secondary metabolite found in abundance in very few plant species
including Nigella sativa L., Monarda fistulosa L., Thymus vulgaris L. and Satureja montana …
including Nigella sativa L., Monarda fistulosa L., Thymus vulgaris L. and Satureja montana …
[HTML][HTML] Natural bioactive compounds targeting epigenetic pathways in cancer: a review on alkaloids, terpenoids, quinones, and isothiocyanates
N El Omari, S Bakrim, M Bakha, JM Lorenzo… - Nutrients, 2021 - mdpi.com
Cancer is one of the most complex and systemic diseases affecting the health of mankind,
causing major deaths with a significant increase. This pathology is caused by several risk …
causing major deaths with a significant increase. This pathology is caused by several risk …
[HTML][HTML] Nutritional Value and Preventive Role of Nigella sativa L. and Its Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and …
J Ansary, F Giampieri, TY Forbes-Hernandez, L Regolo… - Molecules, 2021 - mdpi.com
In recent times, scientific attention has been paid to different foods and their bioactive
components for the ability to inhibit the onset and progress of different types of cancer …
components for the ability to inhibit the onset and progress of different types of cancer …
Effect of aberrant DNA methylation on cancer stem cell properties
DNA methylation, as an epigenetic mechanism, occurs by adding a methyl group of
cytosines in position 5 by DNA methyltransferases and has essential roles in cellular …
cytosines in position 5 by DNA methyltransferases and has essential roles in cellular …
[HTML][HTML] Natural bioactive compounds targeting histone deacetylases in human cancers: recent updates
Cancer is a complex pathology that causes a large number of deaths worldwide. Several
risk factors are involved in tumor transformation, including epigenetic factors. These factors …
risk factors are involved in tumor transformation, including epigenetic factors. These factors …
[HTML][HTML] Epigenetic role of thymoquinone: impact on cellular mechanism and cancer therapeutics
Highlights•Thymoquinone is a natural product with anticancer activity.•Thymoquinone can
methylate or demethylate DNA.•Thymoquinone can interfere with the histone acetylation …
methylate or demethylate DNA.•Thymoquinone can interfere with the histone acetylation …
[HTML][HTML] Chemopreventive and anticancer effects of thymoquinone: cellular and molecular targets
R Gomathinayagam, JH Ha, M Jayaraman… - Journal of cancer …, 2020 - ncbi.nlm.nih.gov
Thymoquinone (TQ) is a bioactive component derived from the seeds of Nigella sativa that
are commonly as black cumin. Evidences indicate that the medicinal properties of TQ have …
are commonly as black cumin. Evidences indicate that the medicinal properties of TQ have …
[HTML][HTML] Thymoquinone-loaded ethosome with breast cancer potential: optimization, in vitro and biological assessment
Ethosomes are most commonly used vesicular delivery system compared to other lipidic
vesicles due to its ethanolic content. Thymoquinone (TQ), the main biologically active …
vesicles due to its ethanolic content. Thymoquinone (TQ), the main biologically active …
Natural products in the reprogramming of cancer epigenetics
R Irshad, M Husain - Toxicology and Applied Pharmacology, 2021 - Elsevier
Owing to the technological advancements, including next generation sequencing, the
significance of deregulated epigenetic mechanisms in cancer initiation, progression and …
significance of deregulated epigenetic mechanisms in cancer initiation, progression and …
[HTML][HTML] Thymoquinone in autoimmune diseases: Therapeutic potential and molecular mechanisms
Autoimmune diseases (AUDs) are a multifactorial disease, among which rheumatoid
arthritis, systemic lupus erythematosus and multiple sclerosis are more prevalent. Several …
arthritis, systemic lupus erythematosus and multiple sclerosis are more prevalent. Several …