Staphylococcus aureus, a bacterial commensal of the human nares and skin, is a frequent
cause of soft tissue and bloodstream infections. A hallmark of staphylococcal infections is …

Foot ulcer is a common complication in diabetic subjects and infection of these wounds
contributes to increased rates of morbidity and mortality. Diabetic foot infections are caused …

Staphylococcus aureus causes many types of human infections and syndromes—most
notably skin and soft tissue infections. Abscesses are a frequent manifestation of S. aureus …

The neutrophil is the major phagocyte and the final effector cell of the innate immunity, with a
primary role in the clearance of extracellular pathogens. Using the broad array of cytokines …

In post-natal life the inflammatory response is an inevitable consequence of tissue injury.
Experimental studies established the dogma that inflammation is essential to the …

Staphylococcus aureus, a Gram-positive bacterium colonizing nares, skin, and the
gastrointestinal tract, frequently invades the skin, soft tissues, and bloodstreams of humans …

Staphylococcus aureus can cause superficial skin infections and, occasionally, deep-seated
infections that entail spread through the blood stream. The organism expresses several …

Microbes found on the skin are usually regarded as pathogens, potential pathogens or
innocuous symbiotic organisms. Advances in microbiology and immunology are revising our …

Abstract The angiopoietins Ang-1 and Ang-2 have been identified as ligands of the receptor
tyrosine kinase Tie-2 (refs.,). Paracrine Ang-1–mediated activation of Tie-2 acts as a …

The pathogen Staphylococcus aureus is well adapted to its human host. Neutrophil-
mediated killing is a crucial defense system against S. aureus; however, the pathogen has …