The gut microbiome in Alzheimer's disease: what we know and what remains to be explored

S Chandra, SS Sisodia, RJ Vassar - Molecular neurodegeneration, 2023 - Springer
Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …

Role of sleep deprivation in immune-related disease risk and outcomes

S Garbarino, P Lanteri, NL Bragazzi… - Communications …, 2021 - nature.com
Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …

[HTML][HTML] Gut microbiota in obesity

BN Liu, XT Liu, ZH Liang, JH Wang - World journal of …, 2021 - ncbi.nlm.nih.gov
Obesity is a major global health problem determined by heredity and environment, and its
incidence is increasing yearly. In recent years, increasing evidence linking obesity to the gut …

Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Adipose tissue inflammation and metabolic dysfunction in obesity

T Kawai, MV Autieri, R Scalia - American Journal of …, 2021 - journals.physiology.org
Several lines of preclinical and clinical research have confirmed that chronic low-grade
inflammation of adipose tissue is mechanistically linked to metabolic disease and organ …

The sleep-immune crosstalk in health and disease

L Besedovsky, T Lange, M Haack - Physiological reviews, 2019 - journals.physiology.org
Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

Sleep, circadian rhythm, and gut microbiota

BA Matenchuk, PJ Mandhane, AL Kozyrskyj - Sleep Medicine Reviews, 2020 - Elsevier
From asthma and heart disease to diabetes and obesity, the human microbiome plays a role
in the pathogenesis of each chronic health condition plaguing today's society. Recent work …

[HTML][HTML] Gut microbiome diversity is associated with sleep physiology in humans

RP Smith, C Easson, SM Lyle, R Kapoor, CP Donnelly… - PloS one, 2019 - journals.plos.org
The human gut microbiome can influence health through the brain-gut-microbiome axis.
Growing evidence suggests that the gut microbiome can influence sleep quality. Previous …

[HTML][HTML] Sleep loss can cause death through accumulation of reactive oxygen species in the gut

A Vaccaro, YK Dor, K Nambara, EA Pollina, C Lin… - Cell, 2020 - cell.com
The view that sleep is essential for survival is supported by the ubiquity of this behavior, the
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …