Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …

Multidisciplinary research efforts in the field of drug delivery have led to the development of
a variety of drug delivery systems (DDS) designed for site-specific delivery of diagnostic and …

Delivery of nucleic acids into solid tumor environments remains a pressing challenge. This
study examines the ability of macrophages to horizontally transfer small interfering RNA …

There is an unmet medical need in the area of Parkinson's disease (PD) to develop novel
therapeutic approaches that can stop and reverse the underlying mechanisms responsible …

Nucleic acid delivery for cancer holds extraordinary promise. Increasing expression of tumor
suppressor genes or inhibition of oncogenes in cancer cells has important therapeutic …

Since Jon A. Wolff found skeletal muscle cells being able to express foreign genes and
Russell J. Mumper increased the gene transfection efficiency into the myocytes by adding …

Cell-based drug delivery systems have generated an increasing interest in recent years. We
previously demonstrated that systemically administered macrophages deliver therapeutics …

Thermo‐sensitive hydrogels are considered ideal for applications in the biomedical fields for
their biocompatibility, flexibility, tissue‐like water content, and reversible gelation property …

The paper provides a high-level overview of the use of polymeric micelles, polyion
complexes, cell mediated drug carriers and exosomes in the therapy of cancer and …

US20220088225A1 - Viral transduction using poloxamines - Google Patents
US20220088225A1 - Viral transduction using poloxamines - Google Patents Viral …