The management and treatment of bone cancer pain (BCP) remain significant clinical
challenges, imposing substantial economic burdens on patients and society. Extensive …

Triglycerides are the main storage form of oil in plant seeds. Both fatty acids and
triglycerides possess important functions in the process of plant growth and development. To …

Chemotherapy resistance to colon cancer is an unavoidable obstacle in the clinical
management of the disease. Clitocine, an adenosine analog, played a significant role in the …

Aberrant DNA methylation, as one of the promising biomarkers, is intimately connected to a
variety of genetic and tumor diseases. Herein, we constructed an innovative intra-stimuli …

Both fine particulate matter (PM 2.5) and high-fat diet (HFD) can cause changes in glucose
and lipid metabolisms; however, the mechanism of their combined effects on glucose and …

Abstract Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) represents the
most frequent cause of hepatic disorder, and its progressive form defined as Metabolic …

(1) Background: Hepatoblastoma is the most common primary liver malignancy in children.
During its development, metabolic reprogramming becomes particularly relevant due to the …

Abstract β-Klotho (KLB), a type I transmembrane protein, serves as an obligate co-receptor
determining the tissue-specific actions of endocrine fibroblast growth factors (FGFs). Despite …

Reactive oxygen species (ROS) originate from diverse sources and regulate multiple
signaling pathways within the cellular environment. Their generation is intricately controlled …

The global increase in obesity-related metabolic disorders has led to metabolic dysfunction-
associated steatotic liver disease (MASLD) emerging as one of the most prevalent chronic …