Spin hyperpolarization in modern magnetic resonance
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …
disciplines and in various practical applications, with medical magnetic resonance imaging …
Chemistry of MRI contrast agents: current challenges and new frontiers
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …
performed annually around the world. The contrast agents, which improve diagnostic …
Hyperpolarized Xe NMR signal advancement by metal-organic framework entrapment in aqueous solution
Q Zeng, B Bie, Q Guo, Y Yuan, Q Han… - Proceedings of the …, 2020 - National Acad Sciences
We report hyperpolarized Xe signal advancement by metal-organic framework (MOF)
entrapment (Hyper-SAME) in aqueous solution. The 129Xe NMR signal is drastically …
entrapment (Hyper-SAME) in aqueous solution. The 129Xe NMR signal is drastically …
Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?
V Alterio, A Di Fiore, K D'Ambrosio, CT Supuran… - Chemical …, 2012 - ACS Publications
Carbonic anhydrases (CAs, EC 4.2. 1.1) are ubiquitous metallo-enzymes, present
throughout most living organisms and encoded by five evolutionarily unrelated gene …
throughout most living organisms and encoded by five evolutionarily unrelated gene …
A review of responsive MRI contrast agents: 2005–2014
DV Hingorani, AS Bernstein… - Contrast media & …, 2015 - Wiley Online Library
This review focuses on MRI contrast agents that are responsive to a change in a
physiological biomarker. The response mechanisms are dependent on six physicochemical …
physiological biomarker. The response mechanisms are dependent on six physicochemical …
NMR hyperpolarization techniques of gases
Nuclear spin polarization can be significantly increased through the process of
hyperpolarization, leading to an increase in the sensitivity of nuclear magnetic resonance …
hyperpolarization, leading to an increase in the sensitivity of nuclear magnetic resonance …
Protein recognition using synthetic small-molecular binders toward optical protein sensing in vitro and in live cells
Chemical sensing of amino acids, peptides, and proteins provides fruitful information to
understand their biological functions, as well as to develop the medical and technological …
understand their biological functions, as well as to develop the medical and technological …
Subcellular delivery of hydrogen sulfide using small molecule donors impacts organelle stress
AK Gilbert, MD Pluth - Journal of the American Chemical Society, 2022 - ACS Publications
Hydrogen sulfide (H2S) is an endogenously produced gaseous signaling molecule with
important roles in regulating organelle function and stress. Because of its high reactivity …
important roles in regulating organelle function and stress. Because of its high reactivity …
Xenon for NMR biosensing–inert but alert
L Schröder - Physica Medica, 2013 - Elsevier
NMR studies with hyperpolarized xenon as functionalized sensor or contrast agent recently
made notable progress in developing a new approach for detecting molecular markers and …
made notable progress in developing a new approach for detecting molecular markers and …
Opportunities and challenges with hyperpolarized bioresponsive probes for functional imaging using magnetic resonance
G Angelovski, BJ Tickner, G Wang - Nature Chemistry, 2023 - nature.com
The development of hyperpolarized bioresponsive probes for magnetic resonance imaging
(MRI) applications is an emerging and rapidly growing topic in chemistry. A wide range of …
(MRI) applications is an emerging and rapidly growing topic in chemistry. A wide range of …