Notch signaling pathway: a new target for neuropathic pain therapy
Y Zhang, T Wang, S Wu, L Tang, J Wang… - The Journal of …, 2023 - Springer
The Notch gene, a highly evolutionarily conserved gene, was discovered approximately 110
years ago and has been found to play a crucial role in the development of multicellular …
years ago and has been found to play a crucial role in the development of multicellular …
Highly selective A3 adenosine receptor agonists relieve chronic neuropathic pain
D Salvemini, KA Jacobson - Expert opinion on therapeutic patents, 2017 - Taylor & Francis
(EOTP) covering the patent landscape on novel approaches to target neuropathic pain have
failed to include and discuss our discovery that A3 adenosine receptor (AR) agonists …
failed to include and discuss our discovery that A3 adenosine receptor (AR) agonists …
Neuropathic pain in leprosy: symptom profile characterization and comparison with neuropathic pain of other etiologies
I Raicher, PRNAG Stump, SB Harnik, RA de Oliveira… - Pain …, 2018 - journals.lww.com
Objectives: The aim of this study was to assess whether neuropathic pain in leprosy has
similar symptom profile as neuropathic pain of other etiologies and to retrospectively assess …
similar symptom profile as neuropathic pain of other etiologies and to retrospectively assess …
Thiophenpiperazine amide derivatives as new dual MOR and σ1R ligands for the treatment of pain
Z Fan, Y Xiao, Y Shi, C Hao, Y Chen, G Zhang… - Biochemical and …, 2024 - Elsevier
A new series of thiophenpiperazine amide derivatives as potent dual ligands for the μ-opioid
(MOR) and sigma-1 (σ 1 R) receptors are reported. Compound 23 exhibited good affinity to σ …
(MOR) and sigma-1 (σ 1 R) receptors are reported. Compound 23 exhibited good affinity to σ …
[HTML][HTML] Pulsed radiofrequency alleviated neuropathic pain by down-regulating the expression of substance P in chronic constriction injury rat model
JA Wang, SN Niu, F Luo - Chinese Medical Journal, 2020 - journals.lww.com
Background Pulsed radiofrequency (PRF), as a non-invasive treatment of neuropathic pain
(NP), has been widely administered clinically. Previous studies have shown that PRF has …
(NP), has been widely administered clinically. Previous studies have shown that PRF has …
Chronic neuropathic pain: quality of life, depressive symptoms and distinction between genders
LF Villa, AMR Cunha, LAC Dias, MHD Foss… - BrJP, 2021 - SciELO Brasil
ABSTRACT BACKGROUND AND OBJECTIVES: Neuropathic pain is a chronic pain which
can be accompanied by comorbidities, such as sleep interferences and anxiety. The present …
can be accompanied by comorbidities, such as sleep interferences and anxiety. The present …
Dor crônica neuropática: qualidade de vida, sintomas depressivos e distinção entre os sexos
LF Villa, AMR Cunha, LAC Dias, MHD Foss… - BrJP, 2021 - SciELO Brasil
RESUMO JUSTIFICATIVA E OBJETIVOS: A dor neuropática é uma dor crônica que pode se
apresentar junto com comorbidades, como interferências no sono e ansiedade. O presente …
apresentar junto com comorbidades, como interferências no sono e ansiedade. O presente …
2-pentadecyl-2-oxazoline the oxazoline of Palmitoylethanolamide (PEA-OXA) a new pharmacological strategy for neuropathic pain
E Gugliandolo - 2019 - tesidottorato.depositolegale.it
Background: Animal models of sciatic nerve injury are commonly used to study neuropathic
pain as well as axon regeneration. Inflammation/immune response at the site of nerve lesion …
pain as well as axon regeneration. Inflammation/immune response at the site of nerve lesion …