Plant noncoding RNA transcripts have gained increasing attention in recent years due to
growing evidence that they can regulate developmental plasticity. In this review article, we …

Nucleic acids are powerful triggers of innate immunity and can adopt the Z-conformation, an
unusual left-handed double helix. Here, we studied the biological function (s) of Z-RNA …

ALUs contribute to genetic diversity by altering DNA's linear sequence through
retrotransposition, recombination and repair. ALUs also have the potential to form alternative …

DNA in cells is predominantly B-form double helix. Though certain DNA sequences in vitro
may fold into other structures, such as triplex, left-handed Z form, or quadruplex DNA, the …

Chromosome inheritance depends on centromeres, epigenetically specified regions of
chromosomes. While conventional human centromeres are known to be built of long tandem …

Z-DNA, a left-handed double helical DNA is structurally different from the most abundant B-
DNA. Z-DNA has been known to play a significant role in transcription and genome stability …

DNA cruciform structures play an important role in the regulation of natural processes
including gene replication and expression, as well as nucleosome structure and …

Naturally occurring poly (purine· pyrimidine) rich regions in the human genome are prone to
adopting non-canonical DNA structures such as intramolecular triplexes (ie, H-DNA). Such …

Computational methods to predict Z-DNA regions are in high demand to understand the
functional role of Z-DNA. The previous state-of-the-art method Z-Hunt is based on statistical …

Diverse mechanisms for DNA-protein recognition have been elucidated in numerous atomic
complex structures from various protein families. These structural data provide an invaluable …