Emerging findings suggest that brain-derived neurotrophic factor (BDNF) serves widespread
roles in regulating energy homeostasis by controlling patterns of feeding and physical …

Neurotrophins are a well-known family of neurotrophic factors that play an important role
both in the central and peripheral nervous systems, where they modulate neuronal survival …

Background Research on mesenchymal stromal cells has created high expectations for a
variety of therapeutic applications. Extensive propagation to yield enough mesenchymal …

Background Nerve injuries are debilitating, leading to long-term motor deficits.
Remyelination and axonal growth are supported and enhanced by growth factor and …

Motoneurons axotomized by peripheral nerve injuries experience profound changes in their
synaptic inputs that are associated with a neuroinflammatory response that includes local …

Neurodegenerative diseases are questions that modern therapeutics can still not answer.
Great milestones have been achieved regarding liver, heart, skin, kidney and other types of …

Mesenchymal stem cells have been proven to be potentially effective in the treatment of a
large variety of diseases, including neurodegenerative disorders. Of these, cerebellar ataxia …

The present study investigates the effects of xenotransplantation of Adipose Tissue
Mesenchymal Stem Cells (AT-MSCs) in animals after ventral root avulsion. AT-MSC has …

Inflammatory response contributes to brain injury after ischemia and reperfusion (I/R). Our
previous literature has shown isoquercetin plays an important role in protecting against …

Background Treatment of spinal cord injury is dependent on neuronal survival, appropriate
synaptic circuit preservation, and inflammatory environment management. In this sense …