The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) or without (CRSsNP) are
chronic respiratory diseases. These two disorders often co-exist based on common …

Abstract Background Structural variations (SVs) in individual genomes are major
determinants of complex traits, including adaptability to environmental variables. The …

Abstract Ca2+ entry via Ca2+ release-activated Ca2+ (CRAC) channels is a predominant
mechanism of intracellular Ca2+ elevation in immune cells. Here we show the …

Immune checkpoint inhibition (ICI) has revolutionized cancer treatment; however, only a
subset of patients benefit long term. Therefore, methods for identification of novel checkpoint …

Ethnopharmacological relevance Jingfang granules (JF), one famous traditional Chinese
formula in “She Sheng Zhong Miao Fang” written by Shi-Che Zhang during the Ming …

Background Type 2 innate lymphoid cells (ILC2s) are relevant players in type 2 asthma.
They initiate eosinophil infiltration and airway hyperreactivity (AHR) through cytokine …

Type 2 immunity mediates the immune responses against parasites and allergic stimuli.
Evidence from studies of cell lines and animals implies that neuromedin U (NmU) acts as a …

A dysregulated type 2 immune response is one of the fundamental causes of allergic
asthma. Although Th2 cells are undoubtedly central to the pathogenesis of allergic asthma …

Lung epithelial lining fluid (ELF) harbors a variety of proteins that influence homeostatic and
stress responses in the airspaces. Exosomes, nano-sized extracellular vesicles, contain …