A cross-study analysis of drug response prediction in cancer cell lines

F Xia, J Allen, P Balaprakash, T Brettin… - Briefings in …, 2022 - academic.oup.com
To enable personalized cancer treatment, machine learning models have been developed
to predict drug response as a function of tumor and drug features. However, most algorithm …

Machine learning for bioinformatics and neuroimaging

A Serra, P Galdi, R Tagliaferri - Wiley Interdisciplinary Reviews …, 2018 - Wiley Online Library
Machine Learning (ML) is a well‐known paradigm that refers to the ability of systems to learn
a specific task from the data and aims to develop computer algorithms that improve with …

[HTML][HTML] Anticancer Effect of PtIIPHENSS, PtII5MESS, PtII56MESS and their Platinum (IV)-dihydroxy derivatives Against Triple-Negative Breast Cancer and Cisplatin …

MG Elias, S Fatima, TJ Mann, S Karan, M Mikhael… - Cancers, 2024 - ncbi.nlm.nih.gov
Abstract Development of resistance to cisplatin, oxaliplatin and carboplatin remains a
challenge for their use as chemotherapies, particularly in breast and colorectal cancer. Here …

Domain-invariant features for mechanism of action prediction in a multi-cell-line drug screen

JC Boyd, A Pinheiro, E Del Nery, F Reyal… - …, 2020 - academic.oup.com
Motivation High-content screening is an important tool in drug discovery and
characterization. Often, high-content drug screens are performed on one single-cell line. Yet …

[HTML][HTML] Aerosol Immunotherapy with or without Cisplatin for metastatic lung cancer non-small cell lung cancer disease: In vivo Study. A more efficient combination

K Sapalidis, P Zarogoulidis, E Pavlidis, S Laskou… - Journal of …, 2018 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of cancer death after prostate cancer for males and breast
cancer for females. There are novel therapies in the past five years such as; tyrosine kinase …

New phenotypic cytotoxicity assay for ROS-inducing compounds using rat renal epithelial cells

N Uchiyama, T Yukawa, YP Dragan, MP Wagoner… - Toxicology Letters, 2020 - Elsevier
An important mechanism of chemical toxicity is the induction of oxidative stress through the
production of excess reactive oxygen species (ROS). In this study, we show that the level of …

Place du ganglion sentinelle dans les cancers du col utérin débutants

V Balaya, B Guani, H Bonsang-Kitzis, M Deloménie… - Bulletin du …, 2020 - Elsevier
Résumé Le statut ganglionnaire est le facteur pronostique le plus important chez les
patientes atteintes d'un cancer du col utérin aux stades précoces. Le prélèvement du …

[引用][C] Aerosol Immunotherapy with or without Cisplatin for metastatic lung cancer non-small cell lung cancer disease

K Sapalidis, P Zarogoulidis, E Pavlidis, S Laskou… - vivo