The principles and applications of time‐of‐flight mass spectrometry involving instruments
with independent (orthogonal) axes for ion generation and mass analysis are reviewed. This …

Antimicrobial peptides are important host-defense molecules of innate immunity.
Cathelicidins are a diverse family of potent, rapidly acting and broadly effective antimicrobial …

The bactericidal machinery of mammalian neutrophils is built up of many components with
different chemical properties, involving proteins, peptides and oxygen-dependent radicals …

The porcine leukocyte protegrins are a family of cysteine-rich antimicrobial peptides the
primary structures of which combine features of defensins and tachyplesins. We cloned …

This historical review is dedicated to Prof. Lidija Gall. She was awarded the Thomson medal
(2022) for her contribution to the development of electrospray ionization mass spectrometry …

We cloned the genes of three protegrins, a family of cathelin-associated antimicrobial
peptides originally isolated from porcine leukocytes. Each gene comprised 4 exons and 3 …

Retrocyclins are synthetic θdefensins that were reconstructed from genetic blueprints that
had remained unused for at least 7.5 million years. From phylogenetic studies, it appears …

We determined the cysteine connectivity of protegrin PG‐2, a leukocyte‐derived
antimicrobial peptide, by performing sequential enzyme digestions with chymotrypsin and …

Multi drug resistance is a major problem of the twenty first century. In order to combat this
issue, there is an urgent need in the pharmaceutical industry, for novel therapeutic agents …

Cationic antimicrobial peptides are present throughout the plant and animal kingdoms and
bear striking structural and functional similarities across species lines. They provide …