How cancer hijacks the body's homeostasis through the neuroendocrine system
During oncogenesis, cancer not only escapes the body's regulatory mechanisms, but also
gains the ability to affect local and systemic homeostasis. Specifically, tumors produce …
gains the ability to affect local and systemic homeostasis. Specifically, tumors produce …
Targeting the oncogenic transcription factor FOXM1 to improve outcomes in all subtypes of breast cancer
BS Katzenellenbogen, VS Guillen… - Breast Cancer …, 2023 - Springer
Abstract FOXM1 (Forkhead box M1) is an oncogenic transcription factor that is greatly
upregulated in breast cancer and many other cancers where it promotes tumorigenesis, and …
upregulated in breast cancer and many other cancers where it promotes tumorigenesis, and …
FOXM1: A small fox that makes more tracks for cancer progression and metastasis
Transcription factors (TFs) are indispensable for the modulation of various signaling
pathways associated with normal cell homeostasis and disease conditions. Among cancer …
pathways associated with normal cell homeostasis and disease conditions. Among cancer …
Small-molecule inhibitors targeting FOXM1: current challenges and future perspectives in cancer treatments
S Raghuwanshi, AL Gartel - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Forkhead box (FOX) protein M1 (FOXM1) is a critical proliferation-associated transcription
factor (TF) that is aberrantly overexpressed in the majority of human cancers and has also …
factor (TF) that is aberrantly overexpressed in the majority of human cancers and has also …
Preparation of a novel hyaluronic acid-based separable hydrogel microneedle with niacinamide to treat pigment deposition using solvent-free solid-state crosslinking …
J Lv, J Zhao, X Li, G Ling, P Zhang - European Polymer Journal, 2024 - Elsevier
With the increase in age and prolonged exposure to ultraviolet radiation, especially on the
face, pigment deposition often has a negative impact on individuals physically and …
face, pigment deposition often has a negative impact on individuals physically and …
NB compounds are potent and efficacious FOXM1 inhibitors in high-grade serous ovarian cancer cells
C Liu, M Vorderbruggen, C Muñoz-Trujillo… - Journal of Ovarian …, 2024 - Springer
Genetic studies implicate the oncogenic transcription factor Forkhead Box M1 (FOXM1) as a
potential therapeutic target in high-grade serous ovarian cancer (HGSOC). We evaluated …
potential therapeutic target in high-grade serous ovarian cancer (HGSOC). We evaluated …
Examination of the roles of CgTH in tyrosine metabolism and pigmentation of Pacific oyster (Crassostrea gigas)
K Jiang, H Yu, L Kong, S Liu, S Du, Q Li - Aquaculture, 2025 - Elsevier
The visually appealing shell colours and intricate patterns of shellfish not only attract
consumers but also enhance their economic value. Understanding the inheritance pattern of …
consumers but also enhance their economic value. Understanding the inheritance pattern of …
Targeting anti-apoptotic pathways eliminates senescent melanocytes and leads to nevi regression
Human melanocytic nevi (moles) result from a brief period of clonal expansion of
melanocytes. As a cellular defensive mechanism against oncogene-induced hyperplasia …
melanocytes. As a cellular defensive mechanism against oncogene-induced hyperplasia …
Association between glycemic traits and melanoma: a mendelian randomization analysis
YC Zhang, CD Lu, QY Li, JN Shi, J Shi, M Yang - Frontiers in Genetics, 2023 - frontiersin.org
Background: The causation of Glycemic Traits and risks of Melanoma remains unknown. We
used Mendelian Randomization (MR) to assess the links between Glycemic Traits and …
used Mendelian Randomization (MR) to assess the links between Glycemic Traits and …
Stress vesicles are induced by acute mechanical force and precede the commitment of epidermal stem cells to terminal differentiation
The skin has a pronounced ability to adapt to physical changes in the environment by
exhibiting plasticity at the cellular level. Transient mechanical deformations applied to the …
exhibiting plasticity at the cellular level. Transient mechanical deformations applied to the …