Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19

A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …

[HTML][HTML] A comprehensive literature review on the clinical presentation, and management of the pandemic coronavirus disease 2019 (COVID-19)

P Kakodkar, N Kaka, MN Baig - Cureus, 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) is a declared global pandemic. There are
multiple parameters of the clinical course and management of the COVID-19 that need …

[HTML][HTML] Targeting potential drivers of COVID-19: Neutrophil extracellular traps

BJ Barnes, JM Adrover, A Baxter-Stoltzfus… - Journal of Experimental …, 2020 - rupress.org
Disclosures: MR Looney reported" other" from Neutrolis outside the submitted work. RE
Schwartz is a Sponsored Advisory Board Member for Miromatrix Inc. JD Spicer reported …

Vascular occlusion by neutrophil extracellular traps in COVID-19

M Leppkes, J Knopf, E Naschberger, A Lindemann… - …, 2020 - thelancet.com
Background Coronavirus induced disease 2019 (COVID-19) can be complicated by severe
organ damage leading to dysfunction of the lungs and other organs. The processes that …

COVID‐19 and neutrophils: the relationship between hyperinflammation and neutrophil extracellular traps

L Borges, TC Pithon-Curi, R Curi… - Mediators of …, 2020 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) is a virus‐induced respiratory disease that may
progress to acute respiratory distress syndrome (ARDS) and is triggered by …

[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression

G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …

[HTML][HTML] Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID‐19

CS Whyte, GB Morrow, JL Mitchell, P Chowdary… - Journal of Thrombosis …, 2020 - Elsevier
The global pandemic of coronavirus disease 2019 (COVID‐19) is associated with the
development of acute respiratory distress syndrome (ARDS), which requires ventilation in …

[HTML][HTML] Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19

C Radermecker, N Detrembleur, J Guiot… - Journal of Experimental …, 2020 - rupress.org
Infection with SARS-CoV-2 is causing a deadly and pandemic disease called coronavirus
disease–19 (COVID-19). While SARS-CoV-2–triggered hyperinflammatory tissue-damaging …

Neutrophil extracellular traps in the pathology of cancer and other inflammatory diseases

M Herre, J Cedervall, N Mackman… - Physiological …, 2023 - journals.physiology.org
Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

Uncontrolled innate and impaired adaptive immune responses in patients with COVID-19 acute respiratory distress syndrome

S Hue, A Beldi-Ferchiou, I Bendib… - American journal of …, 2020 - atsjournals.org
Rationale: Uncontrolled inflammatory innate response and impaired adaptive immune
response are associated with clinical severity in patients with coronavirus disease (COVID …