INTRODUCTION The cerebral cortex, or neocortex, is critical to key mammalian skills such
as language, sociability, and sensorimotor control. This structure consists of dozens of …

Cerebral cortical development involves a complex series of highly regulated steps to
generate the laminated structure of the adult neocortex. Neuronal migration is a key part of …

Dystroglycanopathy is a collective term referring to muscular dystrophies with abnormal
glycosylation of dystroglycan. At least 18 causative genes of dystroglycanopathy have been …

Vascular networks surrounding individual organs are important for their development,
maintenance, and function; however, how these networks are assembled remains poorly …

Dystroglycan is a cell membrane protein that binds to the extracellular matrix in a variety of
mammalian tissues. The α-subunit of dystroglycan (αDG) is heavily glycosylated, including a …

Recent research has unveiled numerous important functions of protein glycosylation in
development, homeostasis, and diseases. A type of glycosylation taking the center stage is …

The dystroglycan (DG) complex plays a pivotal role for the stabilization of muscles in
Metazoa. It is formed by two subunits, extracellular α-DG and transmembrane β-DG …

Proper neural circuit formation requires the precise regulation of neuronal migration, axon
guidance, and dendritic arborization. Mutations affecting the function of the transmembrane …

Precise regulation of neuronal migration termination is crucial for the establishment of brain
cytoarchitectures. However, little is known about how neurons terminate migration. Here we …

During brainstem development, newborn neurons originating from the rhombic lip embark
on exceptionally long migrations to generate nuclei important for audition, movement, and …