Diploid genomes consist of two homologous copies of chromosomes with one from each
parent while polyploid genomes contain more than two homologous sets of chromosomes …

Over the past 20 years, tremendous advances in sequencing technologies and
computational algorithms have spurred plant genomic research into a thriving era with …

Many tools have been developed for haplotype assembly—the reconstruction of individual
haplotypes using reads mapped to a reference genome sequence. Due to increasing …

Humans are a diploid species that inherit one set of chromosomes paternally and one
homologous set of chromosomes maternally. Unfortunately, most human sequencing …

We describe a method that exploits c ontiguity p reserving t ransposase seq uencing (CPT-
seq) to facilitate the scaffolding of de novo genome assemblies. CPT-seq is an entirely in …

Determining the underlying haplotypes of individual human genomes is an essential, but
currently difficult, step toward a complete understanding of genome function. Fosmid pool …

Genomic information reported as haplotypes rather than genotypes will be increasingly
important for personalized medicine. Current technologies generate diploid sequence data …

Independent determination of both haplotype sequences of an individual genome is
essential to relate genetic variation to genome function, phenotype, and disease. To address …

Although the majority of genes are expressed equally from both alleles, some genes are
differentially expressed. Organisms possess characteristics to preferentially express a …

Motivation: Some economically important plants including wheat and cotton have more than
two copies of each chromosome. With the decreasing cost and increasing read length of …