Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with
recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact …

Depressive disorders can affect up to 350 million people worldwide, and in developed
countries, the percentage of patients with depressive disorders may be as high as 10 …

Introduction Hidradenitis suppurativa (HS) is an autoinflammatory skin disease with a high
unmet need for effective medical management. Clinically, it is characterized by inflammatory …

Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses
during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment …

Considering the role of epidermal keratinocytes, they occupy more than 90% of the
epidermis, form a physical barrier, and also function as innate immune barrier. For example …

Atopic dermatitis represents a complex and multidimensional interaction that represents
potential fields of preventive and therapeutic management. In addition to the treatment …

The NLRP3 inflammasome is upregulated by various agents, such as nuclear factor-kappa
B (NF-κB), lipopolysaccharide (LPS), and adenosine triphosphate (ATP). The NLRP3 …

Atopic dermatitis (AD) represents the most common skin disease characterized by
heterogeneous endophenotypes and a high disease burden. In Europe, six new systemic …

Inflammatory lung diseases represent a persistent burden for patients and the global
healthcare system. The combination of high morbidity,(partially) high mortality and limited …