Role of interleukin-10 in acute brain injuries

JM Garcia, SA Stillings, JL Leclerc, H Phillips… - Frontiers in …, 2017 - frontiersin.org
Interleukin-10 (IL-10) is an important anti-inflammatory cytokine expressed in response to
brain injury, where it facilitates the resolution of inflammatory cascades, which if prolonged …

Aneurysmal subarachnoid hemorrhage and neuroinflammation: a comprehensive review

BP Lucke-Wold, AF Logsdon, B Manoranjan… - International journal of …, 2016 - mdpi.com
Aneurysmal subarachnoid hemorrhage (SAH) can lead to devastating outcomes including
vasospasm, cognitive decline, and even death. Currently, treatment options are limited for …

The importance of early brain injury after subarachnoid hemorrhage

FA Sehba, J Hou, RM Pluta, JH Zhang - Progress in neurobiology, 2012 - Elsevier
Aneurysmal subarachnoid hemorrhage (aSAH) is a medical emergency that accounts for
5% of all stroke cases. Individuals affected are typically in the prime of their lives (mean age …

Biology of intracranial aneurysms: role of inflammation

N Chalouhi, MS Ali, PM Jabbour… - Journal of Cerebral …, 2012 - journals.sagepub.com
Intracranial aneurysms (IAs) linger as a potentially devastating clinical problem. Despite
intense investigation, our understanding of the mechanisms leading to aneurysm …

Systemic inflammation response index and systemic immune-inflammation index for predicting the prognosis of patients with aneurysmal subarachnoid hemorrhage

S Yun, HJ Yi, DH Lee, JH Sung - Journal of Stroke and Cerebrovascular …, 2021 - Elsevier
Objectives Inflammatory response plays a pivotal role in the progress of aneurysmal
subarachnoid hemorrhage (aSAH). As novel inflammatory markers, systemic inflammation …

Vascular adaptation and mechanical homeostasis at tissue, cellular, and sub-cellular levels

JD Humphrey - Cell biochemistry and biophysics, 2008 - Springer
Blood vessels exhibit a remarkable ability to adapt throughout life that depends upon
genetic programming and well-orchestrated biochemical processes. Findings over the past …

Cerebral vasospasm: a review

JM Findlay, J Nisar, T Darsaut - Canadian Journal of Neurological …, 2016 - cambridge.org
Cerebral vasospasm is a prolonged but reversible narrowing of cerebral arteries beginning
days after subarachnoid hemorrhage. Progression to cerebral ischemia is tied mostly to …

Cerebral vasospasm after subarachnoid hemorrhage: the emerging revolution

RL Macdonald, RM Pluta, JH Zhang - Nature clinical practice Neurology, 2007 - nature.com
Cerebral vasospasm is the classic cause of delayed neurological deterioration after
aneurysmal subarachnoid hemorrhage, leading to cerebral ischemia and infarction, and …

Neuroinflammation as a target for intervention in subarachnoid hemorrhage

AL de Oliveira Manoel, RL Macdonald - Frontiers in neurology, 2018 - frontiersin.org
Aneurysmal subarachnoid hemorrhage (SAH) is a sub-type of hemorrhagic stroke
associated with the highest rates of mortality and long-term neurological disabilities. Despite …

Hemodynamic stress, inflammation, and intracranial aneurysm development and rupture: a systematic review

F Signorelli, S Sela, L Gesualdo, S Chevrel, F Tollet… - World neurosurgery, 2018 - Elsevier
Background There seems to be a pathogenetic link between hemodynamics and
inflammatory arterial wall alteration leading to the development and rupture of intracranial …