Vaccine adjuvant uses of poly-IC and derivatives
KAO Martins, S Bavari, AM Salazar - Expert review of vaccines, 2015 - Taylor & Francis
Pathogen-associated molecular patterns (PAMPs) are stand-alone immunomodulators or
'danger signals,'that are increasingly recognized as critical components of many modern …
'danger signals,'that are increasingly recognized as critical components of many modern …
[HTML][HTML] Investigating evolutionary conservation of dendritic cell subset identity and functions
TP Vu Manh, N Bertho, A Hosmalin… - Frontiers in …, 2015 - frontiersin.org
Dendritic cells (DCs) were initially defined as mononuclear phagocytes with a dendritic
morphology and an exquisite efficiency for naïve T-cell activation. DC encompass several …
morphology and an exquisite efficiency for naïve T-cell activation. DC encompass several …
Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than …
C Ma, Y Li, L Wang, G Zhao, X Tao, CTK Tseng, Y Zhou… - Vaccine, 2014 - Elsevier
Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) was originally identified
in Saudi Arabia in 2012. It has caused MERS outbreaks with high mortality in the Middle …
in Saudi Arabia in 2012. It has caused MERS outbreaks with high mortality in the Middle …
[HTML][HTML] Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness …
Human monocyte-derived dendritic cell (MoDC) have been used in the clinic with
moderately encouraging results. Mouse XCR1+ DC excel at cross-presentation, can be …
moderately encouraging results. Mouse XCR1+ DC excel at cross-presentation, can be …
[HTML][HTML] The STING activator c-di-AMP exerts superior adjuvant properties than the formulation poly (I: C)/CpG after subcutaneous vaccination with soluble protein …
J Volckmar, L Knop, S Stegemann-Koniszewski… - Vaccine, 2019 - Elsevier
Vaccination is the most efficient strategy to protect from infectious diseases and the induction
of a protective immune response not only depends on the nature of the antigen, but is also …
of a protective immune response not only depends on the nature of the antigen, but is also …
Devices and formulations for pulmonary vaccination
WF Tonnis, AJ Lexmond, HW Frijlink… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Pulmonary vaccination could be a promising alternative to vaccination by
injection. Administration of a vaccine to the lungs does not require the use of needles, which …
injection. Administration of a vaccine to the lungs does not require the use of needles, which …
Antigen delivery to CD11c+ CD8− dendritic cells induces protective immune responses against experimental melanoma in mice in vivo
K Neubert, CHK Lehmann, L Heger… - The Journal of …, 2014 - journals.aai.org
Dendritic cells (DCs) are central modulators of immune responses and, therefore, interesting
target cells for the induction of antitumor immune responses. Ag delivery to select DC …
target cells for the induction of antitumor immune responses. Ag delivery to select DC …
[HTML][HTML] Targeting the non-structural protein 1 from dengue virus to a dendritic cell population confers protective immunity to lethal virus challenge
HR Henriques, EV Rampazo… - PLoS neglected …, 2013 - journals.plos.org
Dengue is the most prevalent arboviral infection, affecting millions of people every year.
Attempts to control such infection are being made, and the development of a vaccine is a …
Attempts to control such infection are being made, and the development of a vaccine is a …
Advancing immunomodulation by in vivo antigen delivery to DEC-205 and other cell surface molecules using recombinant chimeric antibodies
CA Iberg, D Hawiger - International immunopharmacology, 2019 - Elsevier
A targeted delivery of defined antigens in vivo allows for the probing of relevant functions of
the immune system. Recombinant chimeric antibodies, produced by genetically modifying …
the immune system. Recombinant chimeric antibodies, produced by genetically modifying …
[HTML][HTML] Targeted Delivery of Toxoplasma gondii Antigens to Dendritic Cells Promote Immunogenicity and Protective Efficiency against Toxoplasmosis
Z Lakhrif, A Moreau, B Hérault, A Di-Tommaso… - Frontiers in …, 2018 - frontiersin.org
Toxoplasmosis is a major public health problem and the development of a human vaccine is
of high priority. Efficient vaccination against Toxoplasma gondii requires both a mucosal and …
of high priority. Efficient vaccination against Toxoplasma gondii requires both a mucosal and …