Recent advances in zinc enzymology

WN Lipscomb, N Sträter - Chemical Reviews, 1996 - ACS Publications
Posters and lectures presented at the Seventh International Conference on Bioinorganic
Chemistry (ICBIC) in Lubeck, Germany, last year was divided into 16 sections, including …

Structure and function of type II restriction endonucleases

A Pingoud, A Jeltsch - Nucleic acids research, 2001 - academic.oup.com
More than 3000 type II restriction endonucleases have been discovered. They recognize
short, usually palindromic, sequences of 4–8 bp and, in the presence of Mg2+, cleave the …

Two‐metal ion catalysis in enzymatic Acyl‐and phosphoryl‐transfer reactions

N Sträter, WN Lipscomb, T Klabunde… - … International Edition in …, 1996 - Wiley Online Library
Numerous studies, both in enzymatic and nonenzymatic catalysis, have been undertaken to
understand the way by which metal ions, especially zinc ions, promote the hydrolysis of …

Recognition and cleavage of DNA by type‐II restriction endonucleases

A Pingoud, A Jeltsch - European Journal of Biochemistry, 1997 - Wiley Online Library
Restriction endonucleases are enzymes which recognize short DNA sequences and cleave
the DNA in both strands. Depending on the enzymological properties different types are …

SURVEY AND SUMMARY: holliday junction resolvases and related nucleases: identification of new families, phyletic distribution and evolutionary trajectories

L Aravind, KS Makarova, EV Koonin - Nucleic acids research, 2000 - academic.oup.com
Holliday junction resolvases (HJRs) are key enzymes of DNA recombination. A detailed
computer analysis of the structural and evolutionary relationships of HJRs and related …

Sequence, structure and functional diversity of PD-(D/E) XK phosphodiesterase superfamily

K Steczkiewicz, A Muszewska, L Knizewski… - Nucleic acids …, 2012 - academic.oup.com
Proteins belonging to PD-(D/E) XK phosphodiesterases constitute a functionally diverse
superfamily with representatives involved in replication, restriction, DNA repair and tRNA …

The role of metals in catalysis by the restriction endonuclease Bam HI

H Viadiu, AK Aggarwal - Nature structural biology, 1998 - nature.com
Type II restriction enzymes are characterized by their remarkable specificity and simplicity.
They require only divalent metals (such as Mg 2+ or Mn 2+) as cofactors to catalyze the …

Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA

M Deibert, S Grazulis, G Sasnauskas, V Siksnys… - nature structural …, 2000 - nature.com
The crystal structure of the NgoMIV restriction endonuclease in complex with cleaved DNA
has been determined at 1.6 Å resolution. The crystallographic asymmetric unit contains a …

Catalytic mechanisms of restriction and homing endonucleases

EA Galburt, BL Stoddard - Biochemistry, 2002 - ACS Publications
The catalytic mechanisms of type II restriction endonucleases and homing endonucleases
are discussed and compared. Brief reviews of the chemistry of phosphoryl transfers and …

[HTML][HTML] Unexpected structural diversity in DNA recombination: the restriction endonuclease connection

AB Hickman, Y Li, SV Mathew, EW May, NL Craig… - Molecular cell, 2000 - cell.com
Transposition requires a coordinated series of DNA breakage and joining reactions. The
Tn7 transposase contains two proteins: TnsA, which carries out DNA breakage at the 5 …