A decade of GWAS results in lung cancer
Genome-wide association studies (GWAS) were successful to identify genetic factors
robustly associated with lung cancer. This review aims to synthesize the literature in this field …
robustly associated with lung cancer. This review aims to synthesize the literature in this field …
Epidemiology of lung cancer
AG Schwartz, ML Cote - Lung cancer and personalized medicine: Current …, 2016 - Springer
Lung cancer continues to be one of the most common causes of cancer death despite
understanding the major cause of the disease: cigarette smoking. Smoking increases lung …
understanding the major cause of the disease: cigarette smoking. Smoking increases lung …
Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking
Z Huang, S Sun, M Lee, AY Maslov, M Shi… - Nature …, 2022 - nature.com
Although lung cancer risk among smokers is dependent on smoking dose, it remains
unknown if this increased risk reflects an increased rate of somatic mutation accumulation in …
unknown if this increased risk reflects an increased rate of somatic mutation accumulation in …
Exploring and visualizing large-scale genetic associations by using PheWeb
To the Editor—Advances in genotyping and sequencing technologies, the growing
availability of electronic health records for research use and the emergence of population …
availability of electronic health records for research use and the emergence of population …
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer
Y Wang, JD McKay, T Rafnar, Z Wang, MN Timofeeva… - Nature …, 2014 - nature.com
We conducted imputation to the 1000 Genomes Project of four genome-wide association
studies of lung cancer in populations of European ancestry (11,348 cases and 15,861 …
studies of lung cancer in populations of European ancestry (11,348 cases and 15,861 …
Lung cancer in China: challenges and interventions
J She, P Yang, Q Hong, C Bai - Chest, 2013 - Elsevier
In 2008, lung cancer replaced liver cancer as the number one cause of death among people
with malignant tumors in China. The registered lung cancer mortality rate increased by …
with malignant tumors in China. The registered lung cancer mortality rate increased by …
[HTML][HTML] A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma
MT Landi, N Chatterjee, K Yu, LR Goldin… - The american journal of …, 2009 - cell.com
Three genetic loci for lung cancer risk have been identified by genome-wide association
studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not …
studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not …
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …
chronic obstructive pulmonary disease. We tested genome-wide association with forced …
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12. 12 and 22q12. 2 in Han Chinese
Lung cancer is the leading cause of cancer-related deaths worldwide. To identify genetic
factors that modify the risk of lung cancer in individuals of Chinese ancestry, we performed a …
factors that modify the risk of lung cancer in individuals of Chinese ancestry, we performed a …
Molecular biology of lung cancer: clinical implications
JE Larsen, JD Minna - Clinics in chest medicine, 2011 - chestmed.theclinics.com
Lung cancer is the leading cause of cancer-related death in men and women in the United
States, accounting for approximately 28% of total cancer deaths in 2010 despite comprising …
States, accounting for approximately 28% of total cancer deaths in 2010 despite comprising …