The trypanosomiases consist of a group of important animal and human diseases caused by
parasitic protozoa of the genus Trypanosoma. In sub-Saharan Africa, the final decade of the …

Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …

Trypanosoma cruzi interacts with the different arms of the innate and adaptive host's immune
response in a very complex and flowery manner. The history of host-parasite co-evolution …

The inflammatory response that follows the infection with Trypanosoma cruzi is essential for
host resistance to infection but is also responsible for the diverse pathology observed in …

Despite many years of investigation and discussion, the cause of disease in chronic
Trypanosoma cruzi infection remains a hotly debated topic. The primary point of contention …

Chagas disease affects 7.7 million people and 28 million people are at risk of acquiring the
disease in 15 endemic countries of Latin America. Benznidazole and nifurtimox are drugs …

As a consequence of infection by Trypanosoma cruzi, 30% of victims may develop chronic
Chagas disease, which presents a spectrum of pathology including cardiomyopathy …

In this study, we evaluated the activities of respiratory chain complexes and oxidative
phosphorylation (OXPHOS) capacity of the heart to gain insights into the pathological …

Chagas' disease is a major health problem in Latin America, where it constitutes one of the
leading causes of heart failure. About one fourth of Trypanosoma cruzi-infected individuals …

Chagas heart disease is caused by infection with the protozoan parasite Trypanosoma cruzi.
The apparent absence of parasites from the hearts of most individuals who succumb to this …