Innate immunity in tuberculosis: host defense vs pathogen evasion

CH Liu, H Liu, B Ge - Cellular & molecular immunology, 2017 - nature.com
The major innate immune cell types involved in tuberculosis (TB) infection are
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …

The role of glutathione reductase and related enzymes on cellular redox homoeostasis network

N Couto, J Wood, J Barber - Free radical biology and medicine, 2016 - Elsevier
In this review article we examine the role of glutathione reductase in the regulation,
modulation and maintenance of cellular redox homoeostasis. Glutathione reductase is …

Structure of an endogenous mycobacterial MCE lipid transporter

J Chen, A Fruhauf, C Fan, J Ponce, B Ueberheide… - Nature, 2023 - nature.com
To replicate inside macrophages and cause tuberculosis, Mycobacterium tuberculosis must
scavenge a variety of nutrients from the host,. The mammalian cell entry (MCE) proteins are …

Different modalities of host cell death and their impact on Mycobacterium tuberculosis infection

A Nisa, FC Kipper, D Panigrahy… - … of Physiology-Cell …, 2022 - journals.physiology.org
Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …

Cell death at the cross roads of host-pathogen interaction in Mycobacterium tuberculosis infection

K Mohareer, S Asalla, S Banerjee - Tuberculosis, 2018 - Elsevier
Tuberculosis (TB) continues to be the leading cause of death by any single infectious agent,
accounting for around 1.7 million annual deaths globally, despite several interventions and …

The source and fate of Mycobacterium tuberculosis complex in wastewater and possible routes of transmission

HN Mtetwa, ID Amoah, S Kumari, F Bux, P Reddy - BMC Public Health, 2022 - Springer
Abstract Background The Mycobacterium tuberculosis complex (MTBC) consists of
causative agents of both human and animal tuberculosis and is responsible for over 10 …

Augmentation of the riboflavin-biosynthetic pathway enhances mucosa-associated invariant T (MAIT) cell activation and diminishes Mycobacterium tuberculosis …

RJ Dey, B Dey, M Harriff, ET Canfield, DM Lewinsohn… - MBio, 2022 - Am Soc Microbiol
Mucosa-associated invariant T (MAIT) cells play a critical role in antimicrobial defense.
Despite increased understanding of their mycobacterial ligands and the clinical association …

Androgen receptor gene polymorphism and polycystic ovary syndrome

LH Lin, MCP Baracat, GAR Maciel, JM Soares Jr… - International Journal of …, 2013 - Elsevier
BACKGROUND: Polycystic ovary syndrome (PCOS) is characterized by ovulatory
dysfunction and hyperandrogenism. Its etiopathology is not well understood but genetic …

[HTML][HTML] The ATP-Binding Cassette (ABC) Transport Systems in Mycobacterium tuberculosis: Structure, Function, and Possible Targets for Therapeutics

M Cassio Barreto de Oliveira, A Balan - Biology, 2020 - mdpi.com
Simple Summary Mycobacterium tuberculosis is a bacterium of great medical importance
because it causes tuberculosis, a disease that affects millions of people worldwide. Two …

The Genome of Mycobacterium Africanum West African 2 Reveals a Lineage-Specific Locus and Genome Erosion Common to the M. tuberculosis Complex

SD Bentley, I Comas, JM Bryant, D Walker… - PLoS neglected …, 2012 - journals.plos.org
Background M. africanum West African 2 constitutes an ancient lineage of the M.
tuberculosis complex that commonly causes human tuberculosis in West Africa and has an …