Recent advances in the formulation of PLGA microparticles for controlled drug delivery

E Lagreca, V Onesto, C Di Natale, S La Manna… - Progress in …, 2020 - Springer
Polymeric microparticles (MPs) are recognized as very popular carriers to increase the
bioavailability and bio-distribution of both lipophilic and hydrophilic drugs. Among different …

Nanoparticle entry into cells; the cell biology weak link

G Griffiths, J Gruenberg, M Marsh, J Wohlmann… - Advanced Drug Delivery …, 2022 - Elsevier
Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

Photothermal therapy of tuberculosis using targeting pre-activated macrophage membrane-coated nanoparticles

B Li, W Wang, L Zhao, Y Wu, X Li, D Yan, Q Gao… - Nature …, 2024 - nature.com
Conventional antibiotics used for treating tuberculosis (TB) suffer from drug resistance and
multiple complications. Here we propose a lesion–pathogen dual-targeting strategy for the …

Polysarcosine-functionalized lipid nanoparticles for therapeutic mRNA delivery

SS Nogueira, A Schlegel, K Maxeiner… - ACS Applied Nano …, 2020 - ACS Publications
Polysarcosine (pSar) is a polypeptoid based on the endogenous amino acid sarcosine (N-
methylated glycine), which has previously shown potent stealth properties. Here, lipid …

Quantitative Comparison of Gold Nanoparticle Delivery via the Enhanced Permeation and Retention (EPR) Effect and Mesenchymal Stem Cell (MSC)-Based …

L Xu, M Xu, X Sun, N Feliu, L Feng, WJ Parak, S Liu - ACS nano, 2023 - ACS Publications
There are still some gaps in existing knowledge in the field of cancer nanotheranostics, eg.,
the efficiency of nanoparticle-loaded cells for targeted delivery. In the current study, gold …

Cardiovascular toxicity assessment of polyethylene nanoplastics on developing zebrafish embryos

M Sun, R Ding, Y Ma, Q Sun, X Ren, Z Sun, J Duan - Chemosphere, 2021 - Elsevier
Environmental exposure to nanoplastics is inevitable as the application of nanoplastics in
our daily life is more and more extensively. So, the adverse effects of nanoplastics on human …

Fluoropolymer-MOF Hybrids with Switchable Hydrophilicity for 19F MRI-Monitored Cancer Therapy

Q Wang, Y Yu, Y Chang, X Xu, M Wu, GR Ediriweera… - ACS …, 2023 - ACS Publications
Cancer theranostics that combines cancer diagnosis and therapy is a promising approach
for personalized cancer treatment. However, current theranostic strategies suffer from low …

Nanomaterials meet zebrafish: Toxicity evaluation and drug delivery applications

HR Jia, YX Zhu, QY Duan, Z Chen, FG Wu - Journal of Controlled Release, 2019 - Elsevier
With the rapid development of engineered nanomaterials for various applications, in vivo
toxicological studies for evaluating the potential hazardous effects of nanomaterials on …

Infection microenvironment-activated core-shell nanoassemblies for photothermal/chemodynamic synergistic wound therapy and multimodal imaging

Y Qi, S Ren, J Ye, Y Tian, G Wang, S Zhang, L Du, Y Li… - Acta Biomaterialia, 2022 - Elsevier
The development of intelligent designs of new antibacterial modalities for diagnosing and
treating chronic multidrug-resistant bacterial infections is an urgent need, but achieving the …

Nanostructured antimicrobial peptides: The last push towards clinics

JV Carratalá, N Serna, A Villaverde, E Vázquez… - Biotechnology …, 2020 - Elsevier
Peptide drugs hold great potential for the treatment of infectious diseases due to their
unconventional mechanisms of action, biocompatibility, biodegradability and ease of …