A watch-and-wait approach for locally advanced rectal cancer after a clinical complete response following neoadjuvant chemoradiation: a systematic review and meta …

F Dossa, TR Chesney, SA Acuna… - The lancet …, 2017 - thelancet.com
Background A watch-and-wait approach for patients with clinical complete response to
neoadjuvant chemoradiation could avoid the morbidity of conventional surgery for rectal …

Predictive and prognostic molecular biomarkers for response to neoadjuvant chemoradiation in rectal cancer

D Dayde, I Tanaka, R Jain, MC Tai… - International journal of …, 2017 - mdpi.com
The standard of care in locally advanced rectal cancer is neoadjuvant chemoradiation
(nCRT) followed by radical surgery. Response to nCRT varies among patients and …

Rectal cancer, version 2.2022, NCCN clinical practice guidelines in oncology

AB Benson, AP Venook, MM Al-Hawary, N Azad… - Journal of the National …, 2022 - jnccn.org
This selection from the NCCN Guidelines for Rectal Cancer focuses on management of
malignant polyps and resectable nonmetastatic rectal cancer because important updates …

Rectal cancer, version 2.2018, NCCN clinical practice guidelines in oncology

AB Benson, AP Venook, MM Al-Hawary… - Journal of the National …, 2018 - jnccn.org
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Rectal Cancer
address diagnosis, staging, surgical management, perioperative treatment, management of …

MR imaging of rectal cancer: radiomics analysis to assess treatment response after neoadjuvant therapy

N Horvat, H Veeraraghavan, M Khan, I Blazic, J Zheng… - Radiology, 2018 - pubs.rsna.org
Purpose To investigate the value of T2-weighted–based radiomics compared with
qualitative assessment at T2-weighted imaging and diffusion-weighted (DW) imaging for …

Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study

J Tie, JD Cohen, Y Wang, L Li, M Christie, K Simons… - Gut, 2019 - gut.bmj.com
Objective For patients with locally advanced rectal cancer (LARC), adjuvant chemotherapy
selection following surgery remains a major clinical dilemma. Here, we investigated the …

Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO …

C Rödel, U Graeven, R Fietkau, W Hohenberger… - The Lancet …, 2015 - thelancet.com
Background Preoperative chemoradiotherapy with infusional fluorouracil, total mesorectal
excision surgery, and postoperative chemotherapy with fluorouracil was established by the …

Predicting distant metastasis and chemotherapy benefit in locally advanced rectal cancer

Z Liu, X Meng, H Zhang, Z Li, J Liu, K Sun… - Nature …, 2020 - nature.com
Distant metastasis (DM) is the main cause of treatment failure in locally advanced rectal
cancer. Adjuvant chemotherapy is usually used for distant control. However, not all patients …

An MRI deep learning model predicts outcome in rectal cancer

X Jiang, H Zhao, OL Saldanha, S Nebelung, C Kuhl… - Radiology, 2023 - pubs.rsna.org
Background Deep learning (DL) models can potentially improve prognostication of rectal
cancer but have not been systematically assessed. Purpose To develop and validate an MRI …

Tumor regression grading after preoperative chemoradiotherapy as a prognostic factor and individual-level surrogate for disease-free survival in rectal cancer

E Fokas, P Ströbel, R Fietkau, M Ghadimi… - JNCI: Journal of the …, 2017 - academic.oup.com
Background We investigated tumor regression grading (TRG) as a prognostic marker and
individual-level surrogate for disease-free survival (DFS) in patients with rectal carcinoma …