Non syndromic orofacial clefts specifically non-syndromic cleft lip/palate are one of the most
common craniofacial malformation among birth defects in human having multifactorial …

The etiology of non‐syndromic oral clefts (NSOFC) is complex with genetics, genomics,
epigenetics, and stochastics factors playing a role. Several approaches have been applied …

Orofacial clefts (OFCs) are among the most common birth defects and impart a significant
burden on afflicted individuals and their families. It is increasingly understood that many …

Abstract Background Structural variants (SVs) such as deletions, duplications, and insertions
are known to contribute to phenotypic variation but remain challenging to identify and …

Background Previous studies have found that children born with a non-syndromic orofacial
cleft have lower-than-average educational attainment. Differences could be due to a genetic …

Nonsyndromic orofacial clefts (OFCs) are a common birth defect and are phenotypically
heterogenous in the structure affected by the cleft—cleft lip (CL) and cleft lip and palate …

As one of the most common structural birth defects, orofacial clefts (OFCs) have been
studied for decades, and recent studies have demonstrated that there are genetic …

Non-syndromic cleft lip and/or palate (NSCL/P) is a congenital malformation with a
prevalence of 1: 700 births. It has a multifactorial etiology. Human craniofacial development …

Non-syndromic cleft lip with or without cleft palate (nsCL/P) is a common congenital facial
malformation with a multifactorial etiology. Genome-wide association studies (GWASs) have …

Non-syndromic cleft lip with/without cleft palate (nsCL/P) is one of the most common birth
defects and has a multifactorial etiology. To date, over 45 loci harboring common risk …