Photo-triggered destabilization of nanoscopic vehicles by dihydroindolizine for enhanced anticancer drug delivery in cervical carcinoma

P Singh, S Choudhury, S Kulanthaivel, D Bagchi… - Colloids and Surfaces B …, 2018 - Elsevier
The efficacy and toxicity of drugs depend not only on their potency but also on their ability to
reach the target sites in preference to non-target sites. In this regards destabilization of …

Unraveling the role of monoolein in fluidity and dynamical response of a mixed cationic lipid bilayer

P Singh, VK Sharma, S Singha, V García Sakai… - Langmuir, 2019 - ACS Publications
The maintenance of cell membrane fluidity is of critical importance for various cellular
functions. At lower temperatures when membrane fluidity decreases, plants and …

Deciphering the response of asymmetry in the hydrophobic chains of novel cationic lipids towards biological function

D Mukherjee, P Singh, T Rakshit… - Physical Chemistry …, 2020 - pubs.rsc.org
Cationic liposomes, a type of non-viral vectors, often play the important biological function of
delivering nucleic acids during cell transfection. Variations in the molecular architecture of di …

[HTML][HTML] The effect of anionic dicephalic surfactants on fabrication of varied-core nanocarriers for sustained release of porphyrin photosensitizers

U Bazylińska, R Frąckowiak, Z Brzózka… - Journal of Photochemistry …, 2017 - Elsevier
Double-headed anionic surfactants could provide a profound group of efficient stabilizers of
new template-mediated nanocarriers for effective encapsulation and sustained release of …

A sensitive fluorescent probe for the polar solvation dynamics at protein–surfactant interfaces

P Singh, S Choudhury, S Singha, Y Jun… - Physical Chemistry …, 2017 - pubs.rsc.org
Relaxation dynamics at the surface of biologically important macromolecules is important
taking into account their functionality in molecular recognition. Over the years it has been …

Sensitized ZnO nanorod assemblies to detect heavy metal contaminated phytomedicines: spectroscopic and simulation studies

D Bagchi, TK Maji, S Sardar, P Lemmens… - Physical Chemistry …, 2017 - pubs.rsc.org
The immense pharmacological relevance of the herbal medicine curcumin including anti-
cancer and anti-Alzheimer effects, suggests it to be a superior alternative to synthesised …

Essential dynamics of an effective phototherapeutic drug in a nanoscopic delivery vehicle: Psoralen in ethosomes for biofilm treatment

D Bagchi, S Dutta, P Singh, S Chaudhuri, SK Pal - ACS omega, 2017 - ACS Publications
Appropriate localization of a drug and its structure/functional integrity in a delivery agent
essentially dictates the efficacy of the vehicle and the medicinal activity of the drug. In the …

Modulation of solvation and molecular recognition of a lipid bilayer under dynamical phase transition

P Singh, S Choudhury, VK Sharma, S Mitra… - …, 2018 - Wiley Online Library
It is well accepted in contemporary biology that an∼ 30 Å thick lipid bilayer film around living
cells is a matter of life and death as the film typically delimits the environments that serve as …

Host assisted molecular recognition by human serum albumin: Study of molecular recognition controlled protein/drug mimic binding in a microfluidic channel

D Mukherjee, P Singh, S Singh, DS Roy… - International Journal of …, 2021 - Elsevier
Human serum albumin (HSA) plays a pivotal role in drug release from its delivery vehicles
such as cyclodextrins (CDs) by binding to the drugs. Here molecular recognition and binding …

Ultrafast spectroscopy on DNA-cleavage by endonuclease in molecular crowding

P Singh, S Choudhury, S Dutta, A Adhikari… - International journal of …, 2017 - Elsevier
The jam-packed intracellular environments differ the activity of a biological macromolecule
from that in laboratory environments (in vitro) through a number of mechanisms called …