Since the completion of the human genome project in 2003, extraordinary progress has
been made in genome sequencing technologies, which has led to a decreased cost per …

Comparisons of human genomes show that more base pairs are altered as a result of
structural variation—including copy number variation—than as a result of point mutations …

Real-time quantitative polymerase chain reaction (qPCR) and digital PCR (dPCR) methods
have revolutionized environmental microbiology, yielding quantitative organism-specific …

Nanoliter-sized droplet technology paired with digital PCR (ddPCR) holds promise for highly
precise, absolute nucleic acid quantification. Our comparison of microRNA quantification by …

The outbreak of COVID-19 caused by a novel Coronavirus (termed SARS-CoV-2) has
spread to over 210 countries around the world. Currently, reverse transcription quantitative …

Digital PCR enables the absolute quantitation of nucleic acids in a sample. The lack of
scalable and practical technologies for digital PCR implementation has hampered the …

There is growing interest in digital PCR (dPCR) because technological progress makes it a
practical and increasingly affordable technology. dPCR allows the precise quantification of …

Droplet digital polymerase chain reaction (ddPCR) is a new technology that was recently
commercialized to enable the precise quantification of target nucleic acids in a sample …

A digital assay is one in which the sample is partitioned into many small containers such that
each partition contains a discrete number of biological entities (0, 1, 2, 3,…). A powerful …

Rapid antimicrobial susceptibility testing (AST) is urgently needed for informing treatment
decisions and preventing the spread of antimicrobial resistance resulting from the misuse …