Nuclear P38: roles in physiological and pathological processes and regulation of nuclear translocation
G Maik-Rachline, L Lifshits, R Seger - International journal of molecular …, 2020 - mdpi.com
The p38 mitogen-activated protein kinase (p38MAPK, termed here p38) cascade is a central
signaling pathway that transmits stress and other signals to various intracellular targets in …
signaling pathway that transmits stress and other signals to various intracellular targets in …
Targeting NR4A nuclear receptors to control stromal cell inflammation, metabolism, angiogenesis, and tumorigenesis
D Crean, EP Murphy - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
The NR4A1–NR4A3 (Nur77, Nurr1, and Nor-1) subfamily of nuclear receptors is a group of
immediate early genes induced by a pleiotropy of stimuli including peptide hormones …
immediate early genes induced by a pleiotropy of stimuli including peptide hormones …
[HTML][HTML] FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells
Z Ye, Q Zhuo, Q Hu, X Xu, Z Zhang, W Xu, W Liu, G Fan… - Redox biology, 2021 - Elsevier
FBW7 functions as a tumor suppressor by targeting oncoproteins for degradation. Our
previous study found FBW7 was low expressed in pancreatic cancer due to sustained …
previous study found FBW7 was low expressed in pancreatic cancer due to sustained …
Endogenous Nur77 is a specific indicator of antigen receptor signaling in human T and B cells
JF Ashouri, A Weiss - The Journal of Immunology, 2017 - journals.aai.org
Distinguishing true Ag-stimulated lymphocytes from bystanders activated by the
inflammatory milieu has been difficult. Nur77 is an immediate early gene whose expression …
inflammatory milieu has been difficult. Nur77 is an immediate early gene whose expression …
Nuclear receptor 4A (NR4A) family–orphans no more
S Safe, UH Jin, B Morpurgo, A Abudayyeh… - The Journal of steroid …, 2016 - Elsevier
The orphan nuclear receptors NR4A1, NR4A2 and NR4A3 are immediate early genes
induced by multiple stressors, and the NR4A receptors play an important role in maintaining …
induced by multiple stressors, and the NR4A receptors play an important role in maintaining …
Transcriptional profiling of mammary gland in Holstein cows with extremely different milk protein and fat percentage using RNA sequencing
X Cui, Y Hou, S Yang, Y Xie, S Zhang, Y Zhang… - BMC genomics, 2014 - Springer
Abstract Background Recently, RNA sequencing (RNA-seq) has rapidly emerged as a major
transcriptome profiling system. Elucidation of the bovine mammary gland transcriptome by …
transcriptome profiling system. Elucidation of the bovine mammary gland transcriptome by …
Tim-3 enhances FcεRI-proximal signaling to modulate mast cell activation
BL Phong, L Avery, TL Sumpter, JV Gorman… - Journal of Experimental …, 2015 - rupress.org
T cell (or transmembrane) immunoglobulin and mucin domain protein 3 (Tim-3) has
attracted significant attention as a novel immune checkpoint receptor (ICR) on chronically …
attracted significant attention as a novel immune checkpoint receptor (ICR) on chronically …
Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells
SN Vasilatos, TA Katz, S Oesterreich, Y Wan… - …, 2013 - academic.oup.com
Our previous studies demonstrated that lysine-specific demethylase 1 (LSD1) and histone
deacetylases (HDACs) closely interact in controlling growth of breast cancer cells. However …
deacetylases (HDACs) closely interact in controlling growth of breast cancer cells. However …
Semaphorin 3E suppresses tumor cell death triggered by the plexin D1 dependence receptor in metastatic breast cancers
J Luchino, M Hocine, MC Amoureux, B Gibert, A Bernet… - Cancer cell, 2013 - cell.com
The semaphorin guidance molecules and their receptors, the plexins, are often
inappropriately expressed in cancers. However, the signaling processes mediated by …
inappropriately expressed in cancers. However, the signaling processes mediated by …