Immunopathogenesis of Behcet's disease

B Tong, X Liu, J Xiao, G Su - Frontiers in immunology, 2019 - frontiersin.org
Behcet's disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology
characterized by recurrent episodes of oral aphthous ulcers, genital ulcers, skin lesions …

Understanding uveitis: the impact of research on visual outcomes

MD de Smet, SRJ Taylor, B Bodaghi… - Progress in retinal and …, 2011 - Elsevier
The term uveitis encompasses a very diverse group of inflammatory ocular diseases that
cause a significant burden of legal and economic blindness. Indeed, the socioeconomic …

New insights into the pathogenesis of Behcet's disease

MP de Chambrun, B Wechsler, G Geri, P Cacoub… - Autoimmunity …, 2012 - Elsevier
Behçet's disease (BD) is a recurrent systemic inflammatory disorder of unknown origin
characterized by oral and genital mucous ulcer, uveitis, and skin lesions. Involvement of …

Cytokines and Behcet's disease

ZY Zhou, SL Chen, N Shen, Y Lu - Autoimmunity reviews, 2012 - Elsevier
Behcet's Disease (BD) is a systemic vasculitis of unknown etiology. Increasing studies find
that a sophisticated interlacing cytokine network is closely implicated in the onset, evolution …

Neuro-Behçet syndrome

S Saip, G Akman-Demir, A Siva - Handbook of clinical neurology, 2014 - Elsevier
Behçet syndrome (BS) is an idiopathic chronic relapsing multisystem vascular-inflammatory
disease of unknown origin. As the disease affects many organs and systems and shows a …

Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease

YJ Lee, Y Horie, GR Wallace, YS Choi… - Annals of the …, 2013 - ard.bmj.com
Objectives To identify non-major histocompatibility complex susceptible genes that might
contribute to Behçet's disease (BD). Methods We performed a genome-wide association …

Genetic component of giant cell arteritis

FD Carmona, MA Gonzalez-Gay, J Martín - Rheumatology, 2014 - academic.oup.com
Important steps forwards have been taken during recent years towards the understanding of
the genetic basis of autoimmunity. The increasing number of study cohorts is allowing better …

Genome-Wide Association Study in an Admixed Case Series Reveals IL12A as a New Candidate in Behçet Disease

JH Kappen, C Medina-Gomez, PM Hagen, L Stolk… - PloS one, 2015 - journals.plos.org
Introduction The etiology of Behçet's disease (BD) is unknown, but widely considered an
excessive T-cell mediated inflammatory response in a genetically susceptible host. Recent …

Behcet′ s disease: new concepts in cardiovascular involvements and future direction for treatment

MB Owlia, G Mehrpoor - International Scholarly Research …, 2012 - Wiley Online Library
Behcet's disease (BD) is the only systemic vasculitis involving both arteries and vein in any
sizes. It frequently encounters in rheumatology clinics. It has some major morbidities and …

An update on the genetics of HLA B27-associated acute anterior uveitis

TM Martin, JT Rosenbaum - Ocular immunology and inflammation, 2011 - Taylor & Francis
The discovery of the association of HLA B27 with spondyloarthropathy led to more questions
than answers about the role of this gene in disease susceptibility. The realization that HLA …