Background Accurate and rapid detection of tuberculosis (TB) and drug resistance are
critical for improving patient care and decreasing the spread of TB. Xpert® MTB/RIF assay …

Rapid diagnosis is one key pillar to end tuberculosis (TB). Point-of-care tests (POCTs)
facilitate early detection, immediate treatment, and reduced transmission of TB disease. This …

If tuberculosis (TB) is to be eliminated as a global health problem in the foreseeable future,
improved detection of patients, earlier diagnosis and timely identification of rifampicin …

Background Xpert MTB/RIF and Xpert MTB/RIF Ultra (Xpert Ultra) are World Health
Organization (WHO)‐recommended rapid tests that simultaneously detect tuberculosis and …

Background An accurate biomarker is urgently needed to monitor the response to treatment
in patients with pulmonary tuberculosis. The Xpert MTB/RIF assay is a commercially …

Background Tuberculous meningitis (TBM) is difficult to diagnose promptly. The utility of the
Xpert MTB/RIF test for the diagnosis of TBM remains unclear, and the effect of host-and …

Rationale: Although IFN-γ release assays (IGRAs) are widely used to screen for
Mycobacterium tuberculosis infection in high-income countries, published data on …

ABSTRACT Globally, Xpert MTB/RIF (Xpert) is the most widely used PCR test for the
diagnosis of tuberculosis (TB). Positive results in previously treated patients, which are due …

BACKGROUND: TB meningitis (TBM) diagnosis is difficult and novel diagnostic methods are
needed. The World Health Organization recommends Xpert® MTB/RIF as the initial TBM …

The determinants of Xpert MTB/RIF sensitivity, a widely used PCR test for the diagnosis of
tuberculosis (TB) are poorly understood. We compared culture time-to-positivity (TTP; a …