Anatomy, Function, and Dysfunction of the Right Ventricle: JACC State-of-the-Art Review
J Sanz, D Sánchez-Quintana, E Bossone… - Journal of the American …, 2019 - jacc.org
There is increasing recognition of the crucial role of the right ventricle (RV) in determining
functional status and prognosis in multiple conditions. The normal RV is anatomically and …
functional status and prognosis in multiple conditions. The normal RV is anatomically and …
Pulmonary arterial hypertension: pathogenesis and clinical management
Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …
The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure
The right ventricle (RV) is the major determinant of functional state and prognosis in
pulmonary arterial hypertension. RV hypertrophy (RVH) triggered by pressure overload is …
pulmonary arterial hypertension. RV hypertrophy (RVH) triggered by pressure overload is …
Right ventricular adaptation and failure in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy,
characterized by excess proliferation, apoptosis resistance, inflammation, fibrosis, and …
characterized by excess proliferation, apoptosis resistance, inflammation, fibrosis, and …
World Health Organization Group I pulmonary hypertension: epidemiology and pathophysiology
KW Prins, T Thenappan - Cardiology clinics, 2016 - cardiology.theclinics.com
Pulmonary hypertension (PH) is defined as mean pulmonary arterial pressure(PAP)
measured by right heart catheterization of 25 mm Hg or higher at rest. 1 The most recent …
measured by right heart catheterization of 25 mm Hg or higher at rest. 1 The most recent …
Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and …
Mitochondria are central to cellular metabolism. The metabolic pathways of mitochondria
include fatty acid oxidation, glucose oxidation, and glutaminolysis. The initial step in glucose …
include fatty acid oxidation, glucose oxidation, and glutaminolysis. The initial step in glucose …
A comprehensive review: the evolution of animal models in pulmonary hypertension research; are we there yet?
Pulmonary hypertension (PH) is a disorder that develops as a result of remodeling of the
pulmonary vasculature and is characterized by narrowing/obliteration of small pulmonary …
pulmonary vasculature and is characterized by narrowing/obliteration of small pulmonary …
Mitochondrial dynamics in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is an idiopathic cardiopulmonary disease
characterized by obstruction of small pulmonary arteries. Vascular obstruction is the …
characterized by obstruction of small pulmonary arteries. Vascular obstruction is the …
Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension
KR Stenmark, MG Frid, BB Graham… - Cardiovascular …, 2018 - academic.oup.com
Pulmonary hypertension (PH) is the end result of interaction between pulmonary vascular
tone and a complex series of cellular and molecular events termed 'vascular remodelling' …
tone and a complex series of cellular and molecular events termed 'vascular remodelling' …
Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle
Right ventricular hypertrophy (RVH) and RV failure are major determinants of prognosis in
pulmonary hypertension and congenital heart disease. In RVH, there is a metabolic shift …
pulmonary hypertension and congenital heart disease. In RVH, there is a metabolic shift …