A roadmap for delivering a human musculoskeletal cell atlas

M Baldwin, CD Buckley, F Guilak, P Hulley… - Nature Reviews …, 2023 - nature.com
Advances in single-cell technologies have transformed the ability to identify the individual
cell types present within tissues and organs. The musculoskeletal bionetwork, part of the …

Differences in molecular sampling and data processing explain variation among single-cell and single-nucleus RNA-seq experiments

JT Chamberlin, Y Lee, GT Marth… - Genome Research, 2024 - genome.cshlp.org
A mechanistic understanding of the biological and technical factors that impact transcript
measurements is essential to designing and analyzing single-cell and single-nucleus RNA …

A comprehensive analysis framework for evaluating commercial single-cell RNA sequencing technologies

M De Simone, J Hoover, J Lau, HM Bennett… - Nucleic Acids …, 2024 - academic.oup.com
This study examined nine prominent commercially available single-cell RNA sequencing
(scRNA-seq) kits across four technology groups. Each kit was characterized using …

scPanel: a tool for automatic identification of sparse gene panels for generalizable patient classification using scRNA-seq datasets

Y Xie, J Yang, JF Ouyang… - Briefings in Bioinformatics, 2024 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) technologies can generate transcriptomic profiles
at a single-cell resolution in large patient cohorts, facilitating discovery of gene and cellular …

Comparative transcriptomic analyses of thymocytes using 10x Genomics and Parse scRNA-seq technologies

I Filippov, CS Philip, L Schauser, P Peterson - BMC genomics, 2024 - Springer
Background Single-cell RNA sequencing experiments commonly use 10x Genomics (10x)
kits due to their high-throughput capacity and standardized protocols. Recently, Parse …

[PDF][PDF] 单细胞RNA 测序技术在水产养殖动物上的应用

于红, 林茜, 李琪 - 水产学报, 2024 - aquaticjournal.com
单细胞RNA 测序技术是生命科学领域中的革命性技术, 为动植物的细胞异质性图谱构建,
细胞谱系追踪, 免疫响应机制解析等研究提供了强有力的工具. 近年来, 单细胞RNA …

Single-Molecule Barcoding Technology for Single-Cell Genomics

I Garcia-Bassets, G Mo, Y Xia, TC Wu, I Mekuria… - bioRxiv, 2024 - biorxiv.org
Recent advances in barcoding technologies have significantly enhanced the scalability of
single-cell genomic experiments. However, large-scale experiments are still rare due to high …

Comparative Analysis of Commercial Single-Cell RNA Sequencing Technologies

M De Simone, J Hoover, J Lau, H Bennett, B Wu… - bioRxiv, 2024 - biorxiv.org
This study evaluates ten commercially available single-cell RNA sequencing (scRNA-seq)
approaches across four technology groups: Emulsion-based kits from 10x Genomics and …

Comparing the impact of sample multiplexing approaches for single-cell RNA-sequencing on downstream analysis using cerebellar organoids

K Sarieva, T Kagermeier, V Lysenkov, Z Yentuer… - bioRxiv, 2024 - biorxiv.org
Sample multiplexing provides a solution to limited sample throughput in single-cell RNA
sequencing (scRNA-seq) experiments. Different strategies for multiplexing are commercially …

Machine Learning Predictions Surpass Individual mRNAs as a Proxy of Single-cell Protein Expression

J Fisher, O Wood, S Bullers, L Murray, L Li… - bioRxiv, 2024 - biorxiv.org
Expansive repositories of single-cell RNA-seq data are now available for large-scale
transcriptomics analysis at single-cell resolution. However, proteomics data are relatively …