Seronegative autoimmune diseases: A challenging diagnosis

MV Lenti, CM Rossi, F Melazzini, M Gastaldi… - Autoimmunity …, 2022 - Elsevier
Autoimmune diseases (AID) are increasingly prevalent conditions which comprise more
than 100 distinct clinical entities that are responsible for a great disease burden worldwide …

[HTML][HTML] Seronegative antiphospholipid syndrome: refining the value of “non-criteria” antibodies for diagnosis and clinical management

P Pignatelli, E Ettorre, D Menichelli, A Pani, F Violi… - …, 2020 - ncbi.nlm.nih.gov
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by
arterial and venous thrombotic manifestations and/or pregnancy-related complications in …

GAPSS: the global anti-phospholipid syndrome score

S Sciascia, G Sanna, V Murru, D Roccatello… - …, 2013 - academic.oup.com
Objective. To develop and validate a risk score [global APS score (GAPSS)] derived from the
combination of independent risk for thrombosis and pregnancy loss (PL), taking into account …

14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends

ML Bertolaccini, O Amengual, L Andreoli, T Atsumi… - Autoimmunity …, 2014 - Elsevier
Current classification criteria for definite Antiphospholipid Syndrome (APS) require the use
of three laboratory assays to detect antiphospholipid antibodies (aCL, anti-β2GPI and LA) in …

Infertility in women with systemic autoimmune diseases

J Khizroeva, C Nalli, V Bitsadze, A Lojacono… - Best Practice & …, 2019 - Elsevier
Infertility consists by definition in” failure to achieve a clinical pregnancy after 12 months or
more of regular unprotected intercourse” while the term subfertility means a delay to achieve …

[PDF][PDF] International consensus guidelines on anticardiolipin and anti–2-glycoprotein I testing

G Lakos, EJ Favaloro, EN Harris, PL Meroni… - Arthritis & …, 2012 - researchgate.net
Standardized enzyme-linked immunosorbent assays (ELISAs) for anticardiolipin (aCL) and
anti–2-glycoprotein I (anti-2GPI), though required for diagnosis of the antiphospholipid …

[HTML][HTML] Laboratory diagnosis of antiphospholipid syndrome: insights and hindrances

A Vandevelde, KMJ Devreese - Journal of Clinical Medicine, 2022 - mdpi.com
Diagnosis of antiphospholipid syndrome (APS) requires the presence of a clinical criterion
(thrombosis and/or pregnancy morbidity), combined with persistently circulating …

Current treatment of antiphospholipid syndrome: lights and shadows

G Espinosa, R Cervera - Nature Reviews Rheumatology, 2015 - nature.com
For patients with antiphospholipid syndrome (APS), the consensus is to treat those who
develop thrombosis with long-term oral anticoagulation therapy and to prevent obstetric …

[HTML][HTML] Antiphosphatidylserine/prothrombin antibodies (aPS/PT) as potential diagnostic markers and risk predictors of venous thrombosis and obstetric complications …

H Shi, H Zheng, YF Yin, QY Hu, JL Teng… - Clinical Chemistry and …, 2018 - degruyter.com
Background: The aim of the study was to determine the prevalence and clinical associations
of antiphosphatidylserine/prothrombin antibodies (aPS/PT) with thrombosis and pregnancy …

[HTML][HTML] Antiphospholipid syndrome in 2014: more clinical manifestations, novel pathogenic players and emerging biomarkers

PL Meroni, CB Chighizola, F Rovelli… - Arthritis research & …, 2014 - Springer
The clinical spectrum of the anti-phospholipid syndrome (APS) is not limited to vascular
thrombosis or miscarriages but includes additional manifestations that cannot be explained …