Seronegative autoimmune diseases: A challenging diagnosis
Autoimmune diseases (AID) are increasingly prevalent conditions which comprise more
than 100 distinct clinical entities that are responsible for a great disease burden worldwide …
than 100 distinct clinical entities that are responsible for a great disease burden worldwide …
[HTML][HTML] Seronegative antiphospholipid syndrome: refining the value of “non-criteria” antibodies for diagnosis and clinical management
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by
arterial and venous thrombotic manifestations and/or pregnancy-related complications in …
arterial and venous thrombotic manifestations and/or pregnancy-related complications in …
GAPSS: the global anti-phospholipid syndrome score
S Sciascia, G Sanna, V Murru, D Roccatello… - …, 2013 - academic.oup.com
Objective. To develop and validate a risk score [global APS score (GAPSS)] derived from the
combination of independent risk for thrombosis and pregnancy loss (PL), taking into account …
combination of independent risk for thrombosis and pregnancy loss (PL), taking into account …
14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends
Current classification criteria for definite Antiphospholipid Syndrome (APS) require the use
of three laboratory assays to detect antiphospholipid antibodies (aCL, anti-β2GPI and LA) in …
of three laboratory assays to detect antiphospholipid antibodies (aCL, anti-β2GPI and LA) in …
Infertility in women with systemic autoimmune diseases
J Khizroeva, C Nalli, V Bitsadze, A Lojacono… - Best Practice & …, 2019 - Elsevier
Infertility consists by definition in” failure to achieve a clinical pregnancy after 12 months or
more of regular unprotected intercourse” while the term subfertility means a delay to achieve …
more of regular unprotected intercourse” while the term subfertility means a delay to achieve …
[PDF][PDF] International consensus guidelines on anticardiolipin and anti–2-glycoprotein I testing
Standardized enzyme-linked immunosorbent assays (ELISAs) for anticardiolipin (aCL) and
anti–2-glycoprotein I (anti-2GPI), though required for diagnosis of the antiphospholipid …
anti–2-glycoprotein I (anti-2GPI), though required for diagnosis of the antiphospholipid …
[HTML][HTML] Laboratory diagnosis of antiphospholipid syndrome: insights and hindrances
A Vandevelde, KMJ Devreese - Journal of Clinical Medicine, 2022 - mdpi.com
Diagnosis of antiphospholipid syndrome (APS) requires the presence of a clinical criterion
(thrombosis and/or pregnancy morbidity), combined with persistently circulating …
(thrombosis and/or pregnancy morbidity), combined with persistently circulating …
Current treatment of antiphospholipid syndrome: lights and shadows
G Espinosa, R Cervera - Nature Reviews Rheumatology, 2015 - nature.com
For patients with antiphospholipid syndrome (APS), the consensus is to treat those who
develop thrombosis with long-term oral anticoagulation therapy and to prevent obstetric …
develop thrombosis with long-term oral anticoagulation therapy and to prevent obstetric …
[HTML][HTML] Antiphosphatidylserine/prothrombin antibodies (aPS/PT) as potential diagnostic markers and risk predictors of venous thrombosis and obstetric complications …
H Shi, H Zheng, YF Yin, QY Hu, JL Teng… - Clinical Chemistry and …, 2018 - degruyter.com
Background: The aim of the study was to determine the prevalence and clinical associations
of antiphosphatidylserine/prothrombin antibodies (aPS/PT) with thrombosis and pregnancy …
of antiphosphatidylserine/prothrombin antibodies (aPS/PT) with thrombosis and pregnancy …
[HTML][HTML] Antiphospholipid syndrome in 2014: more clinical manifestations, novel pathogenic players and emerging biomarkers
PL Meroni, CB Chighizola, F Rovelli… - Arthritis research & …, 2014 - Springer
The clinical spectrum of the anti-phospholipid syndrome (APS) is not limited to vascular
thrombosis or miscarriages but includes additional manifestations that cannot be explained …
thrombosis or miscarriages but includes additional manifestations that cannot be explained …