Diarylheptanoid: A privileged structure in drug discovery

DJ Sun, LJ Zhu, YQ Zhao, YQ Zhen, L Zhang, CC Lin… - Fitoterapia, 2020 - Elsevier
Privileged structures are widely used in the process of drug design, and provide an effective
template in medicinal chemistry. Diarylheptanoids are a class of structurally distinctive …

Myrica esculenta Buch.-Ham.(ex D. Don): a review on its phytochemistry, pharmacology and nutritional potential

G Ahmad, SU Khan, SA Mir, MJ Iqbal… - … Chemistry & High …, 2022 - ingentaconnect.com
Myrica esculenta is an important ethnomedicinal plant used in the traditional system of
medicine and as an important nutraceutical. Several studies on the plant justify its use in …

Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism

S Shen, Q Liao, J Liu, R Pan… - Journal of cachexia …, 2019 - Wiley Online Library
Background Muscle atrophy and weakness are adverse effects of high dose or the sustained
usage of glucocorticoids. Loss of mitochondria and degradation of protein are highly …

Proscillaridin A promotes oxidative stress and ER stress, inhibits STAT3 activation, and induces apoptosis in A549 lung adenocarcinoma cells

A Maryam, T Mehmood, Q Yan, Y Li… - … medicine and cellular …, 2018 - Wiley Online Library
Cardiac glycosides are natural compounds used for the treatment of cardiovascular
disorders. Although originally prescribed for cardiovascular diseases, more recently, they …

An overview of the nutritional value, health properties, and future challenges of Chinese bayberry

S Zhang, Z Yu, L Sun, H Ren, X Zheng, S Liang, X Qi - PeerJ, 2022 - peerj.com
Chinese bayberry (CB) is among the most popular and valuable fruits in China owing to its
attractive color and unique sweet/sour taste. Recent studies have highlighted the nutritional …

Improved oral bioavailability of myricitrin by liquid self-microemulsifying drug delivery systems

N Man, Q Wang, H Li, M Adu-Frimpong, C Sun… - Journal of drug delivery …, 2019 - Elsevier
This study aimed to prepare a self-microemulsifying drug delivery system loaded with
myricitrin (M-SMEDDS) to improve the low oral bioavailability of myricitrin. Prepared M …

Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator

P Lyu, S Li, Y Han, S Shen, Z Feng, P Hao, Z Li… - Bioorganic …, 2023 - Elsevier
Herein, we synthesized an affinity-based probe of myricanol (pMY) with a photo-affinity cross-
linker to initiate a bioconjugation reaction, which was applied for target identification in live …

[HTML][HTML] Protective effects of Myrica rubra flavonoids against hypoxia/reoxygenation-induced cardiomyocyte injury via the regulation of the PI3K/Akt/GSK3β pathway

M Wang, Y Liu, RL Pan, RY Wang… - International …, 2019 - spandidos-publications.com
Myrica rubra is well known for its delicious taste and high nutritional value. The present
study investigated the potential protective effects and mechanisms of M. rubra flavonoids …

Biological Activities of Triterpenoids and Phenolic Compounds from Myrica cerifera Bark

J Zhang, S Yamada, E Ogihara, M Kurita… - Chemistry & …, 2016 - Wiley Online Library
Seven triterpenoids, 1–7, two diarylheptanoids, 8 and 9, four phenolic compounds, 10–13,
and three other compounds, 14–16, were isolated from the hexane and Me OH extracts of …

Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance

MD Martin, L Calcul, C Smith, UK Jinwal… - ACS chemical …, 2015 - ACS Publications
We previously discovered that one specific scalemic preparation of myricanol (1), a
constituent of Myrica cerifera (bayberry/southern wax myrtle) root bark, could lower the …