Diarylheptanoid: A privileged structure in drug discovery
DJ Sun, LJ Zhu, YQ Zhao, YQ Zhen, L Zhang, CC Lin… - Fitoterapia, 2020 - Elsevier
Privileged structures are widely used in the process of drug design, and provide an effective
template in medicinal chemistry. Diarylheptanoids are a class of structurally distinctive …
template in medicinal chemistry. Diarylheptanoids are a class of structurally distinctive …
Myrica esculenta Buch.-Ham.(ex D. Don): a review on its phytochemistry, pharmacology and nutritional potential
Myrica esculenta is an important ethnomedicinal plant used in the traditional system of
medicine and as an important nutraceutical. Several studies on the plant justify its use in …
medicine and as an important nutraceutical. Several studies on the plant justify its use in …
Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism
Background Muscle atrophy and weakness are adverse effects of high dose or the sustained
usage of glucocorticoids. Loss of mitochondria and degradation of protein are highly …
usage of glucocorticoids. Loss of mitochondria and degradation of protein are highly …
Proscillaridin A promotes oxidative stress and ER stress, inhibits STAT3 activation, and induces apoptosis in A549 lung adenocarcinoma cells
A Maryam, T Mehmood, Q Yan, Y Li… - … medicine and cellular …, 2018 - Wiley Online Library
Cardiac glycosides are natural compounds used for the treatment of cardiovascular
disorders. Although originally prescribed for cardiovascular diseases, more recently, they …
disorders. Although originally prescribed for cardiovascular diseases, more recently, they …
An overview of the nutritional value, health properties, and future challenges of Chinese bayberry
S Zhang, Z Yu, L Sun, H Ren, X Zheng, S Liang, X Qi - PeerJ, 2022 - peerj.com
Chinese bayberry (CB) is among the most popular and valuable fruits in China owing to its
attractive color and unique sweet/sour taste. Recent studies have highlighted the nutritional …
attractive color and unique sweet/sour taste. Recent studies have highlighted the nutritional …
Improved oral bioavailability of myricitrin by liquid self-microemulsifying drug delivery systems
N Man, Q Wang, H Li, M Adu-Frimpong, C Sun… - Journal of drug delivery …, 2019 - Elsevier
This study aimed to prepare a self-microemulsifying drug delivery system loaded with
myricitrin (M-SMEDDS) to improve the low oral bioavailability of myricitrin. Prepared M …
myricitrin (M-SMEDDS) to improve the low oral bioavailability of myricitrin. Prepared M …
Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator
Herein, we synthesized an affinity-based probe of myricanol (pMY) with a photo-affinity cross-
linker to initiate a bioconjugation reaction, which was applied for target identification in live …
linker to initiate a bioconjugation reaction, which was applied for target identification in live …
[HTML][HTML] Protective effects of Myrica rubra flavonoids against hypoxia/reoxygenation-induced cardiomyocyte injury via the regulation of the PI3K/Akt/GSK3β pathway
M Wang, Y Liu, RL Pan, RY Wang… - International …, 2019 - spandidos-publications.com
Myrica rubra is well known for its delicious taste and high nutritional value. The present
study investigated the potential protective effects and mechanisms of M. rubra flavonoids …
study investigated the potential protective effects and mechanisms of M. rubra flavonoids …
Biological Activities of Triterpenoids and Phenolic Compounds from Myrica cerifera Bark
J Zhang, S Yamada, E Ogihara, M Kurita… - Chemistry & …, 2016 - Wiley Online Library
Seven triterpenoids, 1–7, two diarylheptanoids, 8 and 9, four phenolic compounds, 10–13,
and three other compounds, 14–16, were isolated from the hexane and Me OH extracts of …
and three other compounds, 14–16, were isolated from the hexane and Me OH extracts of …
Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance
We previously discovered that one specific scalemic preparation of myricanol (1), a
constituent of Myrica cerifera (bayberry/southern wax myrtle) root bark, could lower the …
constituent of Myrica cerifera (bayberry/southern wax myrtle) root bark, could lower the …