Targeting cell signaling in allergic asthma

SS Athari - Signal transduction and targeted therapy, 2019 - nature.com
Asthma is chronic inflammation of the airways characterized by airway hyper-
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …

[HTML][HTML] FOXC1: an emerging marker and therapeutic target for cancer

B Han, N Bhowmick, Y Qu, S Chung, AE Giuliano… - Oncogene, 2017 - nature.com
Abstract The Forkhead box C1 (FOXC1) transcription factor is involved in normal embryonic
development and regulates the development and function of many organs. Most recently, a …

Meta-analysis of miRNA expression profiles for prostate cancer recurrence following radical prostatectomy

E Pashaei, E Pashaei, M Ahmady, M Ozen, N Aydin - PloS one, 2017 - journals.plos.org
Background Prostate cancer (PCa) is a leading reason of death in men and the most
diagnosed malignancies in the western countries at the present time. After radical …

OSCC exosomes regulate miR‐210‐3p targeting EFNA3 to promote oral cancer angiogenesis through the PI3K/AKT pathway

H Wang, L Wang, X Zhou, X Luo, K Liu… - BioMed research …, 2020 - Wiley Online Library
This study is aimed at determining how oral squamous cell carcinoma (OSCC) regulates the
angiogenesis of HUVECs through miR‐210‐3p expression and exploring the relationship …

MALAT 1 induces tongue cancer cells' EMT and inhibits apoptosis through Wnt/β‐catenin signaling pathway

J Liang, L Liang, K Ouyang, Z Li… - Journal of oral pathology …, 2017 - Wiley Online Library
Background MALAT 1 is recognized as an oncogenic lnc RNA in various malignancies.
However, its expression and function in oral tongue squamous cell carcinoma are still …

Inflammatory mediators in oral cancer: pathogenic mechanisms and diagnostic potential

SE Niklander - Frontiers in Oral Health, 2021 - frontiersin.org
Approximately 15% of cancers are attributable to the inflammatory process, and growing
evidence supports an association between oral squamous cell carcinoma (OSCC) and …

Knockdown of long non-coding RNA XIST increases blood–tumor barrier permeability and inhibits glioma angiogenesis by targeting miR-137

H Yu, Y Xue, P Wang, X Liu, J Ma, J Zheng, Z Li, H Cai… - Oncogenesis, 2017 - nature.com
Antiangiogenic therapy plays a significant role in combined glioma treatment. However, poor
permeability of the blood–tumor barrier (BTB) limits the transport of chemotherapeutic …

MicroRNAs in human tongue squamous cell carcinoma: From pathogenesis to therapeutic implications

OF Karatas, M Oner, A Abay, A Diyapoglu - Oral oncology, 2017 - Elsevier
Being one of the most aggressive cancers of oral cavity, tongue squamous cell carcinoma
(TSCC) constitutes 41% of all oral carcinomas. Despite considerable improvements in …

Therapeutically targeting cancers that overexpress FOXC1: A transcriptional driver of cell plasticity, partial EMT, and cancer metastasis

T Ray, T Ryusaki, PS Ray - Frontiers in Oncology, 2021 - frontiersin.org
Metastasis accounts for more than 90% of cancer related mortality, thus the most pressing
need in the field of oncology today is the ability to accurately predict future onset of …

Prognostic factors of oral squamous cell carcinoma in young patients: a systematic review

EF de Morais, RP Mafra, AKG Gonzaga… - Journal of Oral and …, 2017 - Elsevier
Purpose The objective of this review was to identify clinical and pathologic factors related to
the prognosis of oral squamous cell carcinoma in young patients. Materials and Methods We …