Forever young: the first seventy years of ferrocene

P Štěpnička - Dalton Transactions, 2022 - pubs.rsc.org
The discovery of ferrocene,[Fe (η5-C5H5) 2], seventy years ago has significantly influenced
chemical research and provided a key impetus for establishing and rapidly expanding …

Ferrocene-based drugs, delivery nanomaterials and fenton mechanism: state of the art, recent developments and prospects

C Ornelas, D Astruc - Pharmaceutics, 2023 - mdpi.com
Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …

Rational design of molecular phototheranostic platform for NIR-II fluorescence imaging guided chemodynamic-photothermal combined therapy

G Wu, B Sun, Y He, X Tan, Q Pan, S Yang, N Li… - Chemical Engineering …, 2023 - Elsevier
The strategy of synergetic chemodynamic treatment (CDT) and photothermal therapy (PTT)
to improve the anticancer effect has been a hot spot in the field of biomedicine. Herein, a …

Strategies for the nuclear delivery of metal complexes to cancer cells

M Huynh, R Vinck, B Gibert, G Gasser - Advanced Materials, 2024 - Wiley Online Library
The nucleus is an essential organelle for the function of cells. It holds most of the genetic
material and plays a crucial role in the regulation of cell growth and proliferation. Since …

Ferroptosis: The entanglement between traditional drugs and nanodrugs in tumor therapy

K Liu, L Huang, S Qi, S Liu, W Xie, L Du… - Advanced …, 2023 - Wiley Online Library
Ferroptosis is a non‐apoptotic programmed cell death caused by the accumulation of lipid
peroxide. System Xc‐/glutathione peroxidase 4 (GPX4) axis and iron axis are two main …

How does ferrocene correlate with ferroptosis? Multiple approaches to explore ferrocene-appended GPX4 inhibitors as anticancer agents

W Li, J Yu, J Wang, X Fan, X Xu, H Wang, Y Xiong… - Chemical …, 2024 - pubs.rsc.org
Ferroptosis has emerged as a form of programmed cell death and exhibits remarkable
promise for anticancer therapy. However, it is challenging to discover ferroptosis inducers …

[HTML][HTML] Metal-based compounds containing selenium: An appealing approach towards novel therapeutic drugs with anticancer and antimicrobial effects

S Ramos-Inza, D Plano, C Sanmartín - European Journal of Medicinal …, 2022 - Elsevier
In recent years, both metal-based complexes and selenium-containing compounds have
been widely explored for their therapeutic properties due to their roles in biological …

Adding diversity to a diruthenium biscyclopentadienyl scaffold via alkyne incorporation: Synthesis and biological studies

G Bresciani, S Boni, T Funaioli, S Zacchini… - Inorganic …, 2023 - ACS Publications
We report the synthesis and the assessment of the anticancer potential of two series of
diruthenium biscyclopentadienyl carbonyl complexes. Novel dimetallacyclopentenone …

A brief survey on the application of metal-catalyzed azide–alkyne cycloaddition reactions to the synthesis of ferrocenyl-x-1, 2, 3-triazolyl-R (x= none or a linker and R …

K Kowalski - Coordination Chemistry Reviews, 2023 - Elsevier
Cancer is one of the leading causes of death worldwide. This review highlights the
importance of metal-catalyzed azide–alkyne cycloaddition reactions in the synthesis of …

Dual mechanism (sunlight/dark) of the self-assembly nitazoxanide drug on cellulose nanocrystal surface for destroying the Cryptosporidium parvum oocysts

SR Khaleil, NM Mira, NF Ghanem… - International Journal of …, 2023 - Elsevier
Destruction of the cryptosporidium parvum (C. parvum) Oocysts is the main target of the work
via the improvement effect of the nitazoxanide (NTZ) drug by increasing the drug adsorption …