Efficient 3′-pairing renders microRNA targeting less sensitive to mRNA seed accessibility
DM Kosek, E Banijamali, W Becker… - Nucleic Acids …, 2023 - academic.oup.com
MicroRNAs (miRNAs) are short RNAs that post-transcriptionally regulate gene expression
by binding to specific sites in mRNAs. Site recognition is primarily mediated by the seed …
by binding to specific sites in mRNAs. Site recognition is primarily mediated by the seed …
Elucidating microRNA-34a organisation within human Argonaute-2 by dynamic nuclear polarisation-enhanced magic angle spinning NMR
R Dasgupta, W Becker, K Petzold - Nucleic Acids Research, 2024 - academic.oup.com
Understanding mRNA regulation by microRNA (miR) relies on the structural understanding
of the RNA-induced silencing complex (RISC). Here, we elucidate the structural organisation …
of the RNA-induced silencing complex (RISC). Here, we elucidate the structural organisation …
RNA Chemical Probing Reagents and Protein Amino Acids: a Double-Edged Sword
RNA chemical probing experiments are a broadly used method for revealing the structure of
RNA, as well as for identifying protein binding sites. This is beneficial for expanding our …
RNA, as well as for identifying protein binding sites. This is beneficial for expanding our …
Elucidating microRNA-34a organisation within Human Argonaute-2 by DNP MAS NMR
R Dasgupta, W Becker, K Petzold - bioRxiv, 2024 - biorxiv.org
Understanding mRNA regulation by microRNA (miR) relies on the structural understanding
of the RNA-induced silencing complex (RISC). Here, we elucidate the structural organisation …
of the RNA-induced silencing complex (RISC). Here, we elucidate the structural organisation …