Esophageal squamous cell carcinoma (ESCC) is the sixth most common cause of cancer-
related mortality worldwide, with more than half of them occurred in China. Radiotherapy …

Epigenetic changes such as DNA methylation, histone modification, and loss of genome
imprinting play a crucial role in esophageal squamous cell carcinogenesis, along with …

CDH1, a cell adhesion molecule, which plays a key role in maintaining the epithelial
phenotype, is regarded as an invasion-suppressor gene in light of accumulating evidence …

Background Prognosis of esophageal squamous cell carcinoma (ESCC) patients is poor
and the concurrent chemoradiation therapy (CCRT) provided to ESCC patients often failed …

Suprabasin is a recently identified oncoprotein that is upregulated in multiple cancers.
However, the clinical significance and biological role of suprabasin in human esophageal …

Background Silencing of tumor suppressor genes plays a vital role in head and neck
carcinogenesis. In this study we aimed to evaluate aberrant p16INK4a gene promoter …

Esophageal squamous cell carcinoma (ESCC) is highly resistant to chemoradiation therapy.
We aimed to examine whether Nutlin‐3, a molecule that suppresses murine double min 2 …

Esophageal squamous cell carcinoma (ESCC) is the sixth most frequent cause of cancer
death in the world, and cigarette smoke is a key factor in esophageal carcinogenesis. To …

Background Early diagnosis and treatment of esophageal squamous cell dysplasia
(ESCdys) and esophageal squamous cell carcinoma (ESCC) could significantly reduce the …

Colon cancer remains one of the leading causes of cancer-related deaths worldwide.
Transformation of colon epithelial cells into invasive adenocarcinomas has been well known …