The matrix environmental and cell mechanical properties regulate cell migration and contribute to the invasive phenotype of cancer cells

CT Mierke - Reports on Progress in Physics, 2019 - iopscience.iop.org
The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

Partial-volume effect in PET tumor imaging

M Soret, SL Bacharach, I Buvat - Journal of nuclear medicine, 2007 - Soc Nuclear Med
PET has the invaluable advantage of being intrinsically quantitative, enabling accurate
measurements of tracer concentrations in vivo. In PET tumor imaging, indices characterizing …

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani… - Nature, 2017 - nature.com
The early detection of relapse following primary surgery for non-small-cell lung cancer and
the characterization of emerging subclones, which seed metastatic sites, might offer new …

Intratumor heterogeneity characterized by textural features on baseline 18F-FDG PET images predicts response to concomitant radiochemotherapy in esophageal …

F Tixier, CC Le Rest, M Hatt, N Albarghach… - Journal of Nuclear …, 2011 - Soc Nuclear Med
18F-FDG PET is often used in clinical routine for diagnosis, staging, and response to therapy
assessment or prediction. The standardized uptake value (SUV) in the primary or regional …

18F-Fluorodeoxyglucose Positron Emission Tomography Predicts Survival of Patients with Neuroendocrine Tumors

T Binderup, U Knigge, A Loft, B Federspiel… - Clinical Cancer Research, 2010 - AACR
Purpose: 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is currently not
used on a routine basis for imaging of neuroendocrine (NE) tumors. The aim of this study …

Glycolytic enzymes can modulate cellular life span

H Kondoh, ME Lleonart, J Gil, J Wang, P Degan… - Cancer research, 2005 - AACR
An unbiased screen for genes that can immortalize mouse embryonic fibroblasts identified
the glycolytic enzyme phosphoglycerate mutase (PGM). A 2-fold increase in PGM activity …

An introduction to PET-CT imaging

V Kapoor, BM McCook, FS Torok - Radiographics, 2004 - pubs.rsna.org
Cancer is one of the leading causes of morbidity and mortality in developed countries such
as the United States. Complex clinical decisions about treatment of oncologic patients are …

Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute Trials

LK Shankar, JM Hoffman, S Bacharach… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Despite the increasing use of 18F-FDG PET as a biomarker for predicting therapeutic
response, there are no widely accepted standardized protocols for using 18F-FDG PET as a …

Imaging Prostate Cancer: A Multidisciplinary Perspective1

H Hricak, PL Choyke, SC Eberhardt, SA Leibel… - Radiology, 2007 - pubs.rsna.org
The major goal for prostate cancer imaging in the next decade is more accurate disease
characterization through the synthesis of anatomic, functional, and molecular imaging …

Hyperglycemia, a neglected factor during cancer progression

W Duan, X Shen, J Lei, Q Xu, Y Yu, R Li… - BioMed research …, 2014 - Wiley Online Library
Recent evidence from large cohort studies suggests that there exists a higher cancer
incidence in people with type 2 diabetes (DM2). However, to date, the potential reasons for …