Amygdala microcircuits controlling learned fear

S Duvarci, D Pare - Neuron, 2014 - cell.com
We review recent work on the role of intrinsic amygdala networks in the regulation of
classically conditioned defensive behaviors, commonly known as conditioned fear. These …

Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear

HC Pape, D Pare - Physiological reviews, 2010 - journals.physiology.org
The last 10 years have witnessed a surge of interest for the mechanisms underlying the
acquisition and extinction of classically conditioned fear responses. In part, this results from …

[HTML][HTML] Amygdala inhibitory circuits and the control of fear memory

I Ehrlich, Y Humeau, F Grenier, S Ciocchi, C Herry… - Neuron, 2009 - cell.com
Classical fear conditioning is a powerful behavioral paradigm that is widely used to study the
neuronal substrates of learning and memory. Previous studies have clearly identified the …

Rapid strengthening of thalamo-amygdala synapses mediates cue–reward learning

KM Tye, GD Stuber, B De Ridder, A Bonci, PH Janak - Nature, 2008 - nature.com
What neural changes underlie individual differences in goal-directed learning? The lateral
amygdala (LA) is important for assigning emotional and motivational significance to discrete …

Temporal precedence of emotion over attention modulations in the lateral amygdala: Intracranial ERP evidence from a patient with temporal lobe epilepsy

G Pourtois, L Spinelli, M Seeck… - Cognitive, Affective, & …, 2010 - Springer
Previous fMRI studies have reported mixed evidence for the influence of selective attention
on amygdala responses to emotional stimuli, with some studies showing “automatic” …

Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of …

T Müller, D Albrecht, C Gebhardt - Learning & Memory, 2009 - learnmem.cshlp.org
The lateral nucleus of the amygdala (LA) is implicated in emotional and social behaviors.
We recently showed that in horizontal brain slices, activation of NMDA receptors (NMDARs) …

Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress

TS Ramikie, S Patel - Neuroscience, 2012 - Elsevier
The molecular constituents of endocannabinoid (eCB) signaling are abundantly expressed
within the mammalian amygdaloid complex, consistent with the robust role of eCB signaling …

Assignment of model amygdala neurons to the fear memory trace depends on competitive synaptic interactions

D Kim, D Pare, SS Nair - Journal of Neuroscience, 2013 - Soc Neuroscience
We used biophysical modeling to examine a fundamental, yet unresolved, question
regarding how particular lateral amygdala (LA) neurons are assigned to fear memory traces …

Mechanisms contributing to the induction and storage of Pavlovian fear memories in the lateral amygdala

D Kim, D Paré, SS Nair - Learning & Memory, 2013 - learnmem.cshlp.org
The relative contributions of plasticity in the amygdala vs. its afferent pathways to
conditioned fear remain controversial. Some believe that thalamic and cortical neurons …

Hippocampal networks on reliable patterned substrates

MD Boehler, SS Leondopulos, BC Wheeler… - Journal of neuroscience …, 2012 - Elsevier
Toward the goal of reproducible live neuronal networks, we investigated the influence of
substrate patterns on neuron compliance and network activity. We optimized process …