Cyclooxygenase‐2 in cancer: a review

N Hashemi Goradel, M Najafi, E Salehi… - Journal of cellular …, 2019 - Wiley Online Library
Abstract Cyclooxygenase‐2 (COX‐2) is frequently expressed in many types of cancers
exerting a pleiotropic and multifaceted role in genesis or promotion of carcinogenesis and …

Cancer stem cell (CSC) resistance drivers

M Najafi, K Mortezaee, J Majidpoor - Life sciences, 2019 - Elsevier
Cancer stem cells (CSCs) are a population of self-renewal cells with high tumorigenic
potency. CSCs can adopt easily with changes in the nearby milieu, and are more resistant to …

Contribution of regulatory T cells to cancer: A review

M Najafi, B Farhood… - Journal of cellular …, 2019 - Wiley Online Library
Regulatory T cells (Tregs) represent a low number of T‐cell population under normal
conditions, and they play key roles for maintaining immune system in homeostasis. The …

Emerging avenues linking inflammation and cancer

JK Kundu, YJ Surh - Free Radical Biology and Medicine, 2012 - Elsevier
The role of inflammation in carcinogenesis has been extensively investigated and well
documented. Many biochemical processes that are altered during chronic inflammation …

Cancer stem cells: advances in knowledge and implications for cancer therapy

X Chu, W Tian, J Ning, G Xiao, Y Zhou… - … and Targeted Therapy, 2024 - nature.com
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

[PDF][PDF] Long noncoding RNA H19 interacts with polypyrimidine tract‐binding protein 1 to reprogram hepatic lipid homeostasis

C Liu, Z Yang, J Wu, LI Zhang, S Lee, DJ Shin… - …, 2018 - Wiley Online Library
H19 is an imprinted long noncoding RNA abundantly expressed in embryonic liver and
repressed after birth. We show that H19 serves as a lipid sensor by synergizing with the …

Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer

Z Qamri, A Preet, MW Nasser, CE Bass, G Leone… - Molecular cancer …, 2009 - AACR
Cannabinoids have been reported to possess antitumorogenic activity. Not much is known,
however, about the effects and mechanism of action of synthetic nonpsychotic cannabinoids …

d-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis

SC Chaudhary, MS Siddiqui… - Human & …, 2012 - journals.sagepub.com
d-Limonene, a common monoterepene has been shown to have antiproliferative, apoptosis-
inducing and chemopreventive effects. In the present study, we have investigated the effects …

Inhibitory effects of kaempferol on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9

C Li, Y Zhao, D Yang, Y Yu, H Guo… - … and Cell Biology, 2015 - cdnsciencepub.com
Matrix metalloproteinases (MMPs) have been regarded as major critical molecules assisting
tumor cells during metastasis, for excessive ECM (ECM) degradation, and cancer cell …

Novel insights into redox system and the mechanism of redox regulation

X Wang, C Hai - Molecular Biology Reports, 2016 - Springer
In view of the critical role of redox system in numerous physiological and pathophysiological
processes, it is important to clearly understand the family members and regulatory …