To best understand parasite, host, and vector morphologies, host–parasite interactions, and
to develop new drug and vaccine targets, structural data should, ideally, be obtained and …

Chagas disease is a neglected tropical disease and a global public health issue. In terms of
treatment, no progress has been made since the 1960s, when benznidazole and nifurtimox …

The last step of L eishmania intracellular life cycle is the egress of amastigotes from the host
cell and their uptake by adjacent cells. Using multidimensional live imaging of long‐term …

Imaging flow cytometry has been applied to address questions in infection biology, in
particular, infections induced by intracellular pathogens. This methodology, which utilizes …

Recent clinical trials investigating treatment of chronic indeterminate Chagas disease with
two re-purposed azole anti-fungal drugs, posaconazole and ravuconazole, revealed their …

Sphingolipids (SLs) are an integral part of all eukaryotic cellular membranes. In addition,
they have indispensable functions as signalling molecules controlling a myriad of cellular …

An organism that lives on, or within, a host organism and obtains its food from, or at the
expense of its host can be described as a parasite. Antiparasitics are medications that are …

Although imaging the live Trypanosoma cruzi parasite is a routine technique in most
laboratories, identification of the parasite in infected tissues and organs has been hindered …

Bien que les cellules B et leur rôle dans l'immunité humorale soient essentiels à la défense
immunitaire contre de nombreuses infections, au cours de certaines maladies, les cellules B …

Chagas disease is a tropical disease, endemic of the Americas and caused by the
protozoan Trypanosoma cruzi. The classic transmission route of T. cruzi is based on the …