Mechanism of sorafenib resistance associated with ferroptosis in HCC

L Guo, C Hu, M Yao, G Han - Frontiers in pharmacology, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most familiar primary hepatic malignancy with a poor
prognosis. The incidence of HCC and the associated deaths have risen in recent decades …

Oral and Gut Microbial Dysbiosis and Non-alcoholic Fatty Liver Disease: The Central Role of Porphyromonas gingivalis

T Wang, T Ishikawa, M Sasaki, T Chiba - Frontiers in medicine, 2022 - frontiersin.org
Gut microbiota play many important roles, such as the regulation of immunity and barrier
function in the intestine, and are crucial for maintaining homeostasis in living organisms. The …

Identifying proliferative hepatocellular carcinoma at pretreatment CT: implications for therapeutic outcomes after transarterial chemoembolization

Y Bao, JX Li, P Zhou, Y Tong, LZ Wang, DH Chang… - Radiology, 2023 - pubs.rsna.org
Background Hepatocellular carcinomas (HCCs) can be divided into proliferative and
nonproliferative types, which may have implications for outcomes after conventional …

NIR-II emissive AIEgen photosensitizers enable ultrasensitive imaging-guided surgery and phototherapy to fully inhibit orthotopic hepatic tumors

R Jia, H Xu, C Wang, L Su, J Jing, S Xu, Y Zhou… - Journal of …, 2021 - Springer
Accurate diagnosis and effective treatment of primary liver tumors are of great significance,
and optical imaging has been widely employed in clinical imaging-guided surgery for liver …

The double-edged sword role of hydrogen sulfide in hepatocellular carcinoma

H Zhao, Y Zhang, X Fu, C Chen, S Khattak… - Frontiers in …, 2023 - frontiersin.org
With an increasing worldwide prevalence, hepatocellular carcinoma (HCC) is the most
common primary malignant tumor of the liver in the world. It is also the primary reason for …

E2F1-mediated KDM4A-AS1 up-regulation promotes EMT of hepatocellular carcinoma cells by recruiting ILF3 to stabilize AURKA mRNA

HM Shen, D Zhang, P Xiao, B Qu, YF Sun - Cancer Gene Therapy, 2023 - nature.com
Hepatocellular carcinoma (HCC) is a gastrointestinal tumor with high clinical incidence.
Long non-coding RNAs (lncRNAs) play vital roles in modulating the growth and epithelial …

Application of Machine Learning Techniques to Assess Alpha-Fetoprotein at Diagnosis of Hepatocellular Carcinoma

S Gil-Rojas, M Suárez, P Martínez-Blanco… - International Journal of …, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary liver tumor and is associated
with high mortality rates. Approximately 80% of cases occur in cirrhotic livers, posing a …

Novel nanotechnology approaches to overcome drug resistance in the treatment of hepatocellular carcinoma: glypican 3 as a useful target for innovative therapies

M Mossenta, D Busato, M Dal Bo, P Macor… - International Journal of …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the second most lethal tumor, with a 5-year survival rate
of 18%. Early stage HCC is potentially treatable by therapies with curative intent, whereas …

[HTML][HTML] Hereditary hemochromatosis: Temporal trends, sociodemographic characteristics, and independent risk factor of hepatocellular cancer–nationwide …

MB Haider, A Al Sbihi, AJ Chaudhary… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Hereditary hemochromatosis (HH) has an increased risk of hepatocellular
cancer (HCC) both due to genetic risks and iron overload as iron overload can be …

An update on the role of complement in hepatocellular carcinoma

Z Xiao, CLS Yeung, JWP Yam, X Mao - Frontiers in Immunology, 2022 - frontiersin.org
As a main producer of complement, the environment in the liver is greatly affected by the
complement system. Although the complement system is considered to have the ability of …