Current status and advances in untargeted LC-MS tissue lipidomics studies in cardiovascular health

ACA dos Santos, D Vuckovic - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Lipid dysregulation is associated with various disorders, including cardiovascular disease
(CVD). Measuring lipid levels in cardiovascular and adipose tissues is essential for …

Comprehensive analysis of phospholipid in milk and their biological roles as nutrients and biomarkers

J Gu, X Li, G Liao, T Wang, Z Wang, Q Jia… - Critical Reviews in …, 2024 - Taylor & Francis
Phospholipids (PL) have garnered significant attention due to their physiological activities.
Milk and other dairy products are important dietary sources for humans and have been …

Establishing a framework for best practices for quality assurance and quality control in untargeted metabolomics

JD Mosley, TB Schock, CW Beecher, WB Dunn… - Metabolomics, 2024 - Springer
Background Quality assurance (QA) and quality control (QC) practices are key tenets that
facilitate study and data quality across all applications of untargeted metabolomics. These …

[HTML][HTML] Validation of two LCHRMS methods for large-scale untargeted metabolomics of serum samples: Strategy to establish method fitness-for-purpose

S Grijseels, T Vasskog, PJ Heinsvig, TN Myhre… - … of Chromatography A, 2024 - Elsevier
Untargeted metabolomics by LCsingle bondHRMS is a powerful tool to enhance our
knowledge of pathophysiological processes. Whereas validation of a bioanalytical method is …

A global perspective on the status of clinical metabolomics in laboratory medicine–a survey by the IFCC metabolomics working group

E Fux, M Lenski, AK Bendt, JD Otvos… - Clinical Chemistry and …, 2024 - degruyter.com
Objectives Metabolomics aims for comprehensive characterization and measurement of
small molecule metabolites (< 1700 Da) in complex biological matrices. This study sought to …

Online Comprehensive Two-Dimensional Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolic Profiling and Comparison Enabling …

S Wang, Y Zou, M Zhang, X Xu, H Wang… - Journal of Agricultural …, 2024 - ACS Publications
This work was designed for the in-depth characterization and holistic comparison of up to 12
ginseng varieties, which can benefit the development of functional foods and ensure their …

[HTML][HTML] Modulating fine flavor cocoa attributes: Impact of seed-to-bean transformation under controlled conditions on metabolite, volatile and sensory profiles

LD Becerra, RY Ruiz-Pardo, F Vaillant… - Food Research …, 2024 - Elsevier
Fine-flavored chocolates are distinguished by their complex and distinct flavor profiles,
which includes notes such as floral, fruity, nutty, and spicy. This study sought to modulate the …

[HTML][HTML] Characterization of differences in volatile compounds and metabolites of six varieties of potato with different processing properties

W Zhang, L Li, Y Zhao, H Yang, X Zhang, Z Zhang… - Food Chemistry: X, 2024 - Elsevier
Potato is the fourth-most important food crop around the world, and most of the potatoes are
used for foodstuffs and starch products. The aim of this paper is to identify the volatile …

Characterization and identification of chemical components in Si-Ni-San based on UPLC-Q-Orbitrap-MS, HS-SPME-GC–MS, and HS-GC-IMS techniques

Y Zhang, Z Zhang, X Chen, J Chen, J Yin, S Bie… - Microchemical …, 2025 - Elsevier
Abstract Si-Ni-San (SNS) is a traditional Chinese medicine (TCM) formula known for its
efficacy in dispelling evil spirits, relieving depression, dredging the liver and regulating the …

Integration analysis of transcriptome and metabolome revealed the potential mechanism of spermatogenesis in Tibetan sheep (Ovis aries) at extreme high altitude

M Zhang, X An, C Yuan, T Guo, B Xi, J Liu, Z Lu - Genomics, 2024 - Elsevier
Testis has an indispensable function in male reproduction of domestic animals. Numerous
genes and metabolites were related to testicular development and spermatogenesis …